Results 101 to 110 of about 4,374,982 (417)

Oral complications in irradiated head and neck cancer patients - 3D conformal radiotherapy planning vs. 3D conformal radiotherapy planning with magnetic resonance fusion [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2017
Introduction/Objective. The incidence of radiation-induced side effects in patients with head and neck (H&N) cancer depends on the planning technique and the irradiation dose, as well as primary tumor location within the H&N region.
Latinović Miroslav, Mitrić-Asković Milana, Ivanov Olivera, Novaković Mićo, Ličina Jelena   +4 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Implication of Bifurcation of Abdominal Aorta for Radiotherapy Planning for Cervical Cancers [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: External Beam Radiotherapy plays a major role in the management of Carcinoma Cervix. The Radiotherapy treatment portals are designed to adequately cover the gross disease and areas of microscopic spread. The upper border of Radiotherapy
Thiru Raju Arul Ponni, Handanakere Udayashankara Avinash, Manur Gururajachar Janaki, Agrahara Srinivas Kirthi Koushik, Mohan Kumar Somashekar   +4 more
doaj   +1 more source

Adversarial Prediction of Radiotherapy Treatment Machine Parameters [PDF]

arXiv, 2020
Modern external beam cancer radiotherapy applies prescribed radiation doses to tumor targets while minimally affecting nearby vulnerable organs-at-risk (OARs). Creating a treatment plan is difficult and time-consuming with no guarantee of optimality. Knowledge-based planning (KBP) mitigates this uncertainty by guiding planning with probabilistic models
arxiv  

Personalized Radiotherapy Design for Glioblastoma: Integrating Mathematical Tumor Models, Multimodal Scans and Bayesian Inference [PDF]

, 2018
Glioblastoma is a highly invasive brain tumor, whose cells infiltrate surrounding normal brain tissue beyond the lesion outlines visible in the current medical scans. These infiltrative cells are treated mainly by radiotherapy. Existing radiotherapy plans for brain tumors derive from population studies and scarcely account for patient-specific ...
arxiv   +1 more source

Evaluation of 3D Printed Immobilisation Shells for Head and Neck IMRT [PDF]

, 2014
This paper presents the preclinical evaluation of a novel immobilization system for patients undergoing external beam radiation treatment of head and neck tumors.
Applegate, Christopher, Bell, Duncan, Emmens, Daniel, Fisher, Mark, Hulse, Mark, Laycock, Stephen, Ryalat, Mohammad   +6 more
core   +1 more source

Quantum-Inspired Algorithm for Radiotherapy Planning Optimization.

Medical Physics (Lancaster), 2019
PURPOSE Modern inverse radiotherapy treatment planning requires non-convex, large-scale optimizations that must be solved within a clinically feasible timeframe.
J. Pakela, H. Tseng, M. Matuszak, R. T. Ten Haken, D. McShan, I. E. El Naqa   +5 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

A comparison of treatment outcome between fiducial-based and bone-based image guided radiotherapy in prostate cancer patients

Radiation Oncology, 2018
Background and purpose To compare the clinical outcome in prostate cancer patients treated with radiotherapy using two forms of image guidance: bone-based (BB) or fiducial-based (FB).
Aleksandra Napieralska, Wojciech Majewski, Roland Kulik, Grzegorz Głowacki, Leszek Miszczyk   +4 more
doaj   +1 more source

Increased accuracy of planning tools for optimization of dynamic multileaf collimator delivery of radiotherapy through reformulated objective functions [PDF]

Physics in Medicine & Biology 2018, volume 63, number 12, page 125012, 2018
The purpose of this study is to examine in a clinical setting a novel formulation of objective functions for intensity-modulated radiotherapy treatment plan multicriteria optimization (MCO) that we suggested in a recent study. The proposed objective functions are extended with dynamic multileaf collimator (DMLC) delivery constraints from the literature,
arxiv   +1 more source