Results 81 to 90 of about 4,374,982 (417)

Fluence-map generation for prostate intensity-modulated radiotherapy planning using a deep-neural-network

Scientific Reports, 2019
A deep-neural-network (DNN) was successfully used to predict clinically-acceptable dose distributions from organ contours for intensity-modulated radiotherapy (IMRT).
Hoyeon Lee, Hojin Kim, J. Kwak, Young Seok Kim, S. W. Lee, Seungryong Cho, B. Cho   +6 more
semanticscholar   +1 more source

Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer [PDF]

, 2017
Background: Prone whole breast irradiation (WBI) leads to reduced heart and lung doses in breast cancer patients receiving adjuvant radiotherapy. In this feasibility trial, we investigated the prone position for whole breast + lymph node irradiation (WB +
A Berrington de Gonzalez, AM Kirby, Annick Van Greveling, Bert Boute, Bruno Speleers, BT Gielda, BV Offersen, BV Offersen, Chris Monten, CR Jephcott, FR Bartlett, FR Bartlett, G Alco, Giselle Post, Herman Depypere, I Finke, IR Vogelius, IY Jo, J Buijsen, J Reznik, JD Boice Jr, Joris Van de Velde, K Kainz, K Verhoeven, K Verhoeven, L Veldeman, LB Marks, LB Thorsen, Leen Paelinck, Liv Veldeman, LM Sun, M Alonso-Basanta, M Feng, M Stovall, N Dogan, N Mason, P McGale, PD Inskip, Pieter Deseyne, PM Poortmans, RA Sethi, SC Darby, SC Formenti, SC Lymberis, SM Shin, T Grantzau, T Grantzau, T Mulliez, T Mulliez, T Mulliez, T Mulliez, T Viren, TE Merchant, TJ Whelan, Tom Van Hoof, Wilfried De Neve, X Gao   +56 more
core   +2 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Geometrical pre-planning for conformal radiotherapy [PDF]

Acta Oncologica, 2007
The optimum selection of beams and arcs in conformal techniques is of the outmost importance in modern radiotherapy. In this work we give a description of an analytic method to aid optimum selection, which is based on minimizing the intersection between beams and organs at risk (OAR) and on minimizing the intersection between the beam and the planning ...
Ioannis Tsougos, Michael Lahanas, Constantin Kappas, Kiki Theodorou, Dimos Baltas, Eduard Schreibmann   +5 more
openaire   +3 more sources

Systematic endobronchial ultrasound-guided transbronchial needle aspiration improves radiotherapy planning in non-small cell lung cancer

ERJ Open Research, 2019
Objectives Patients suitable for radical chemoradiotherapy for lung cancer routinely have radiotherapy (planning) volumes based on positron emission tomography (PET)-computed tomography (CT) imaging alone.
A. Cole, N. Hardcastle, G. Turgeon, Roshini Thomas, L. Irving, B. Jennings, D. Ball, T. Kron, Daniel P Steinfort, S. Siva   +9 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Evaluation of Dosimetric Efficacy of RapidArc and Intensity-modulated Radiation Therapy Techniques in Head-and-Neck Cancers

Journal of Medical Physics
Aim: This study aims to compare the dosimetric efficacy of RapidArc (RA) and intensity-modulated radiation therapy (IMRT) in the treatment of head-and-neck cancer, focusing on treatment efficiency and organ at risk (OAR) dose.
Pratibha Singh, Manoj Kumar Singh, Atul Mishra   +2 more
doaj   +1 more source

Dosimetric validation of a magnetic resonance image gated radiotherapy system using a motion phantom and radiochromic film. [PDF]

, 2017
PurposeMagnetic resonance image (MRI) guided radiotherapy enables gating directly on the target position. We present an evaluation of an MRI-guided radiotherapy system's gating performance using an MRI-compatible respiratory motion phantom and ...
Berbeco, Brady, Chuang, Fayad, Freislederer, Garibaldi, Giraud, Jin, Keall, Kini, Koch, Lewis, Low, Malinowski, Nioutsikou, Ozhasoglu, Sanders, Seppenwoolde, Shiinoki, Shirato, Smith, Tacke, Voort, Wagman, Wiersma, Wojcieszynski, Wunderink, Yoganathan, Yousefi   +28 more
core   +1 more source

Combining plans in radiotherapy treatment planning

Mathematical and Computer Modelling, 1988
In external beam radiotherapy, an interesting situation occurs when several proposed treatment plans approach the desired dose distribution but none fully satisfies it. A mathematical formulation of such a situation is given here and the question of combining realizable but unacceptable plans is posed.
Morton M. Kligerman, Yair Censor, Martin D. Altschuler, William D. Powlis   +3 more
openaire   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source