Radium-223 use and survival by line of treatment in metastatic castration-resistant prostate cancer: a nationwide population-based register study [PDF]
Acta OncologicaBackground: The role and optimal sequencing of radium-223 in the treatment of metastatic castration-resistant prostate cancer (mCRPC) remain debated.
Charlotte Alverbratt +5 more
doaj +2 more sources
Drug Utilisation of Radium-223 Under Routine Clinical Practice (DIRECT) in Europe: A Post-Authorisation Safety Study [PDF]
Oncology and TherapyIntroduction Radium-223 is indicated for adults with metastatic castration-resistant prostate cancer (mCRPC) and symptomatic bone metastases, without visceral metastases, who progress after at least (≥) two lines of or are ineligible for other systemic ...
Rachel Weinrib +12 more
doaj +2 more sources
Use of remix spent mixed fuel plutonium in the BN-1200 reactor [PDF]
Nuclear Energy and Technology, 2023 The VVER-1000 thermal neutron reactor can operate on mixed uranium-plutonium fuel with a content of reactor-grade plutonium up to 5% with a 100% loaded core. In this case, plutonium burns up to 56% of odd isotopes.
Nikita V. Kovalev +3 more
doaj +3 more sources
A new approach to the recycling of spent nuclear fuel in thermal reactors within the REMIX concept [PDF]
Nuclear Energy and Technology, 2020 A review of simulated nuclear fuel cycles with mixed uranium-plutonium fuel (REMIX) was carried out. The concept of REMIX fuel is one of the options for closing the nuclear fuel cycle (NFC), which makes it possible to recycle uranium and plutonium in ...
Nikita V. Kovalev +3 more
doaj +3 more sources
Naturally Occurring Radioactive Materials in the Soil of Near Basra Oil Company Fields
Iraqi Journal of Industrial Research, 2023 The present study aimed to determine the levels of contamination with Natural Occurring Radioactive Materials NORM in one of the south oil company fields.
M. W. Alhamd +3 more
doaj +1 more source
Molecular Oncology, 2022 Many patients with locally advanced cervical cancer experience recurrence within the radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to identify patients in need of intensified treatment.
Anja Nilsen +10 more
doaj +1 more source
Targeting lung cancer through inhibition of checkpoint kinases
Frontiers in Genetics, 2015 Inhibitors of checkpoint kinases ATR, Chk1 and Wee1 are currently being tested in preclinical and clinical trials. Here, we review the basic principles behind the use of such inhibitors as anticancer agents, and particularly discuss their potential for ...
Randi Gussgard Syljuåsen +4 more
doaj +1 more source
High-Throughput Methods for Detection of Genetic Variation
BioTechniques, 2001 Understanding human genetic variation is currently believed to reveal the cause of individual susceptibility to disease and the large variation observed in response to treatment.
Vessela Nedelcheva Kristensen +3 more
doaj +1 more source
Radiation characteristics of reactor grade platinum group metals [PDF]
Nuclear Energy and TechnologyThe paper examines the radiation characteristics of noble platinum group metals (PGMs) extracted from spent nuclear fuel (SNF) of the VVER-1000 reactor. These are the so-called reactor-grade ruthenium, rhodium and palladium.
Nikita V. Kovalev +3 more
doaj +3 more sources
Solid-Phase Method for Differential Display of Genes Expressed in Hematopoietic Stem Cells
BioTechniques, 1996 A solid-phase differential display method was designed to analyze differential gene expression in samples with low amounts of mRNA. The principle was based on using a biotinylated probe to capture the mRNA and priming both the first-strand synthesis and ...
Ø. Røsok +6 more
doaj +1 more source