Results 151 to 160 of about 5,929 (217)

Impact of BMI and Body Weight on Clinical Outcomes in Psoriasis: A Post Hoc Analysis of the RESOLVE Observational Study

open access: yesJEADV Clinical Practice, EarlyView.
This post‐hoc analysis of the Greek real‐world ReSOLVE study compared clinical and patient‐reported outcomes by body weight (< 100 kg vs. ≥ 100 kg) and BMI over 52 weeks. Patients ≥ 100 kg showed delayed PASI and sPGA responses at W24 and W52, while BMI had little impact. Quality‐of‐life improvements were substantial, though early gains were smaller in
Pantelis Panagakis   +12 more
wiley   +1 more source

On the Nonnegative Rank of Positive Operators

open access: yesMathematische Nachrichten, EarlyView.
ABSTRACT In this paper, we introduce the concept of a nonnegative rank of a positive operator T:X→Y$T: X\rightarrow Y$ between ordered vector spaces. In the case of nonnegative matrices, our definition agrees with the standard definition of a nonnegative rank.
Roman Drnovšek, Marko Kandić
wiley   +1 more source

Nonconstant Positive Steady States for a Predator–Prey System With Signal‐Dependent Diffusion

open access: yesMathematische Nachrichten, EarlyView.
ABSTRACT This paper investigates a highly nonlinear predator–prey reaction–diffusion system featuring signal‐dependent prey diffusion, where the motility of the prey is modulated by a chemical signal released by predators. For unbounded functional responses, we establish the global‐in‐time existence and uniform‐in‐time boundedness of classical ...
Qigang Deng   +3 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés   +2 more
wiley   +1 more source

On the Reconstruction of Planar Vector Fields From Its Longitudinal and Transverse Ray Transform

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We consider a planar vector tomography problem of reconstructing a complex‐valued vector field from the (complete and partial) information of its longitudinal and transverse ray transforms, as well as from one of those transforms and its first moment.
Kamran Sadiq
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

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