Results 161 to 170 of about 5,786 (263)

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Development and Analytical Validation of a Laboratory‐Customized TaqMan‐MGB Probe Method for CYP2C19 Genotyping

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A laboratory‐customized, open‐sequence TaqMan‐MGB probe assay was developed for detecting CYP2C19*2 and CYP2C19*17 polymorphisms using dried blood spot‐derived DNA. The assay demonstrated allele‐specific discrimination, candidate LODs of 1.17 × 102 copies/μL for CYP2C19*2 and 0.94 × 103 copies/μL for CYP2C19*17, and repeatability with CVs below 10%. In
Yaqun Liu   +7 more
wiley   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass   +2 more
wiley   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

Evaluating Reference Evapotranspiration (ETo) Calculation Methods and Quantifying Climate‐Driven Change in Irrigation Demand Across Nepal's Terai

open access: yesInternational Journal of Climatology, EarlyView.
Framework illustrating the comparison of different reference evapotranspiration (ETo) estimation methods and the integration of baseline ETo, crop water requirement (CWR), and irrigation water requirement (IWR) calculations with downscaled CMIP6 climate projections under SSP245 and SSP585 scenarios for the mid‐century and late‐century periods across ...
Umesh Kumar Sujakhu   +3 more
wiley   +1 more source

The German Soil Systematics and the Rationale Behind Its Revision

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background The German Soil Systematics is a pedogenetic classification based on the morphological expressions of pedogenic processes and has been developed over several stages since 1952. The system has successfully been in use for soil classification and soil survey for almost 70 years.
Einar Eberhardt   +3 more
wiley   +1 more source

A talus rock glacier in Nantlle Valley, North Wales

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT Landforms comprising mixtures of fine and coarse sediment and deposited during late glacial times are ubiquitous in the British mountains. In many cases, their interpretation has often proved contentious; as a result, the non‐generic term discrete debris accumulations (DDA) has been used to describe them and, over the last 50 years, some have ...
Stephan Harrison, Ed Anderson
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy