Results 51 to 60 of about 5,929 (217)

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Seasonal Indoor Radon Assessment and Estimation of Cancer Risk: A Case Study of Obafemi Awolowo University Nigeria

Environmental Health Insights
Human exposure to indoor radon has been a subject of continuous concern due to its health implications, especially as it relates to lung cancer. Radon contaminates indoor air quality and poses a significant health threat if not abated/controlled.
Deborah Tolulope Esan, Yinka Ajiboye, Rachel Obed, Babakayode Babajide Olubodun, James Enajero Tobih   +4 more
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

Advanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li, Yu Zhang, Yu Chen, Lingyun He, Xian Shen, Weijian Sun, Hongbo Zhang   +6 more
wiley   +1 more source

Modeling the Relationship Between Radon Anomalies and Seismic Activity Using Artificial Neural Networks and Statistical Methods

Mathematics
The paper presents an approach for detecting anomalies in radon concentration in seismically active areas. It involves training multiple artificial neural networks (ANNs) to predict radon concentration during periods without seismic events.
Kostadin Yotov, Emil Hadzhikolev, Stanka Hadzhikoleva   +2 more
doaj   +1 more source

Seasonal variation of radon and CO2 in the Važecká Cave, Slovakia

Nukleonika, 2020
The continuous monitoring of 222Rn activity concentration, CO2 concentration, and microclimatologic parameters (internal air temperature and relative humidity) in the Važecká Cave (Northern Slovakia) is being carried out at three monitoring stations ...
Smetanová Iveta, Holý Karol, Luhová Ľubica, Csicsay Kristian, Haviarová Dagmar, Kunáková Lucia   +5 more
doaj   +1 more source

Experiments on Nonlocal Fluid‐Flow Metamaterials

Advanced Science, EarlyView.
A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley   +1 more source

Molecular Signatures of HIV‐Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV

Advanced Science, EarlyView.
HIV preferentially infects microglia, activating IL‐17A‐driven IFN‐γ/STAT1, CEBPB, and NF‐κB signaling that converges with cGAS‐STING and Notch–NEURL1 pathways, promoting neuroinflammation, mitochondrial dysfunction, and synaptic impairment. cART suppresses viral replication, attenuates inflammatory signaling, and at least partially restores ...
Karthick Chennakesavan, Malaroviyam Samikkannu, Shreyan Gupta, Olasunkanmi Israel Tayo, Arpan Acharya, James J. Cai, Siddappa N. Byrareddy, Thangavel Samikkannu   +7 more
wiley   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

Estimation of annual effective dose from radon concentration along Main Boundary Thrust (MBT) in Garhwal Himalaya

Journal of Radiation Research and Applied Sciences, 2016
Indoor radon and thoron concentration plays a vital role in the total effective dose in the indoor environments. In the present study, the measurement of indoor radon, soil gas radon concentration and the drinking water radon concentration was carried ...
Tushar Kandari, Sunita Aswal, Mukesh Prasad, A.A. Bourai, R.C. Ramola   +4 more
doaj   +1 more source