Results 121 to 130 of about 272,002 (348)

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Food allergy and mass catering: how to better accommodate allergic school children? Taking stock of an experience conducted in Franche-Comté region, France

open access: yesWorld Allergy Organization Journal, 2020
Laetitia Pellicer-Garcia   +5 more
doaj   +1 more source

Hybrid Raft-PoW Blockchain Consensus Algorithm

open access: yesIEEE Access
The Raft consensus algorithm is widely used in private networks as an alternative to the energy-intensive PoW consensus algorithm in blockchains. The Raft consensus algorithm’s voting mechanism performs well in reliable and well-planned networks ...
Mehtap Kose Ulukok   +2 more
doaj   +1 more source

Mechanical State Analysis of Different Variants of Piled Rafts

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2015
Traditional raft design methods describe unpiled and fully piled rafts. The current paper aims to discuss in-termediate raft design variants when the raft is at the same time partially supported by piles and partially rests on the ground.
Michail Samofalov   +2 more
doaj   +1 more source

The Raft. Descriptive Song [PDF]

open access: green, 1872
Charles J. Rowe, Ciro Pinsuti
openalex   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

open access: yesAdvanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu   +16 more
wiley   +1 more source

Shallot cultivation in tropical climate ecosystems using floating and non-floating systems with different doses of cow manure

open access: yesAdvances in Horticultural Science
Deep swamp is swampland with the longest flooding period, making it challenging for crop cultivation. However, by adopting a floating system, this prolonged duration of flooding can be used for shallot growing.
Susilawati Susilawati   +3 more
doaj   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

Analisa Pondasi Pile Raft Pada Tanah Lunak Dengan Plaxis 2d [PDF]

open access: yes, 2014
Permasalahan penurunan menjadi salah satu masalah yang sering dihadapi para perencana pondasi bangunan dikarenakan oleh kondisi tanah yang lunak. Untuk mengatasi permasalahan yang ada, banyak perencana menggunakan pondasi raft atau pondasi rakit, karena ...
Buntoro, J. (Januar)   +3 more
core   +1 more source

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