Results 51 to 60 of about 272,002 (348)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole

eLife, 2017
Niemann-Pick type C is a storage disease caused by dysfunction of NPC proteins, which transport cholesterol from the lumen of lysosomes to the limiting membrane of that compartment.
Takuma Tsuji, Megumi Fujimoto, Tsuyako Tatematsu, Jinglei Cheng, Minami Orii, Sho Takatori, Toyoshi Fujimoto   +6 more
doaj   +1 more source

Stable, inflatable life raft for high seas rescue operations [PDF]

, 1971
Raft is easily deployed and highly maneuverable in water. It has false bottom of water ballast containers attached to underside, making it exceptionally stable platform from which swimmers can operate.
Barnett, J. H., Jr., Harrison, F., Marak, R., Radnofsky, M. I.   +3 more
core   +1 more source

Heteroatom-Doped Carbon Dots (CDs) as a Class of Metal-Free Photocatalysts for PET-RAFT Polymerization under Visible Light and Sunlight.

Angewandte Chemie, 2018
A key challenge of photoregulated living radical polymerization is developing efficient and robust photocatalysts. Now carbon dots (CDs) have been exploited for the first time as metal-free photocatalysts for visible-light-regulated reversible addition ...
Jingjie Jiang, G. Ye, Zhe Wang, Yuexiang Lu, Jing Chen, K. Matyjaszewski   +5 more
semanticscholar   +1 more source

Detecting Dengue in Flight: Leveraging Machine Learning to Analyze Mosquito Flight Patterns for Infection Detection

Advanced Biology, EarlyView.
Dengue infection alters mosquito flight behavior, enabling detection using machine learning classifiers. This study analyzes 3D flight trajectories and evaluates multiple models, showing that longer sequence lengths improve classification performance.
Nouman Javed, Adam J. López‐Denman, Prasad N. Paradkar, Asim Bhatti   +3 more
wiley   +1 more source

Extracting Raft Aquaculture Areas from Remote Sensing Images via an Improved U-Net with a PSE Structure

Remote Sensing, 2019
Remote sensing has become a primary technology for monitoring raft aquaculture products. However, due to the complexity of the marine aquaculture environment, the boundaries of the raft aquaculture areas in remote sensing images are often blurred, which ...
B. Cui, D. Fei, Guanghui Shao, Yan Lu, J. Chu   +4 more
semanticscholar   +1 more source

Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han, Shota Fujii, André J. van der Vlies, Masoud Ghasemi, Joshua T. Del Mundo, Sarah N. Kiemle, Esther W. Gomez, Enrique D. Gomez, Ralph H. Colby, Urara Hasegawa   +9 more
wiley   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna, Ali, Brown, Bruce, Chen, Enami, Gomez-Puertas, Jeremy Rossman, Johnson, Lai, Leser, Liao, Liu, McCown, McCown, Palese, Pattnaik, Pinto, Rossman, Rossman, Rossman, Rossman, Ruigrok, Schmidt, Takeda, Wang, Wang, Watanabe, Zebedee, Zhang   +29 more
core   +1 more source

Guiding the Design of Organic Photocatalyst for PET-RAFT Polymerization: Halogenated Xanthene Dyes.

Macromolecules, 2018
By examining structurally similar halogenated xanthene dyes, this study establishes a guiding principle for resolving structure-property- performance relationships in the photocontrolled PET-RAFT polymerization system (PET-RAFT: photoinduced electron ...
Chenyu Wu, Nathaniel Corrigan, Chern-Hooi Lim, Kenward Jung, Jian Zhu, G. Miyake, Jiangtao Xu, C. Boyer   +7 more
semanticscholar   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source