A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
Exocarpium Citri Grandis ameliorates alcoholic liver disease by modulation of hepatic lipid metabolism and iron homeostasis. [PDF]
Li YJ +13 more
europepmc +1 more source
Residual magnetization induces pronounced mechanical anisotropy in ultra‐soft magnetorheological elastomers, shaping deformation and actuation even without external magnetic fields. This study introduces a computational‐experimental framework integrating magneto‐mechanical coupling into topology optimization for designing soft magnetic actuators with ...
Carlos Perez‐Garcia +3 more
wiley +1 more source
Engineered prebiotic microcapsules Co-Encapsulating berberine and curcumin Elicit multi-synergistic therapy for ulcerative colitis. [PDF]
Li H +12 more
europepmc +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
Updates on the Role of Innate Immunity's Pattern Recognition Receptors in Vitiligo Pathogenesis and Therapeutic Potential. [PDF]
Feng J +7 more
europepmc +1 more source
DNA Origami‐Templated Aptamer Chiral Structures Realize Cellular Enantioselectivity
Aptamers displayed on tubular DNA origami nanostructures in defined chiral orientations (left‐ or right‐handed) exhibit enantioselective interactions with cell surface target proteins. While the right‐handed configuration supports only transient binding, the left handedness energetically favors protein dimerization and promotes subsequent ...
Tingjie Song +9 more
wiley +1 more source
Retraction: Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis. [PDF]
Frontiers Editorial Office.
europepmc +1 more source
Tuning Pore Size in Porous Graphene Membrane for O2/N2 Separation
Single‐layer graphene membranes featuring N‐functionalized, 0D pores offer a promising platform for O2/N2 separation. The heterogeneity of functional groups at the pore edge is dynamically tunable, enabling precise tuning of the pore limiting diameter and gas transport.
Kuang‐Jung Hsu +5 more
wiley +1 more source

