Abstract Lesbian, gay, bisexual, transgender, queer or questioning, intersex, and/or asexual (LGBTQIA+) individuals are critically underrepresented in science, technology, engineering, and math (STEM) workplaces and often face negative workplace experiences, such as social isolation and pressures to conceal their LGBTQIA+ identity.
Charlotte E. Moser +2 more
wiley +1 more source
Genome-Guided Discovery of Vaccine Targets for a Multi-Epitope Construct Against Multidrug-Resistant Enterobacter cloacae. [PDF]
Aljumaa MA +3 more
europepmc +1 more source
Abstract Polymetallic sulfide deposits produced at hydrothermal vent fields are targets for mining exploitation along the Mid‐Atlantic Ridge, threatening the functioning and resilience of vent ecosystems that provide multiple ecosystem services. Knowledge about connectivity between vents will inform conservation practices.
E. Portanier +10 more
wiley +1 more source
Computational modeling and characterization methods for rotating magnetic nanochain-enhanced lateral flow immunoassays. [PDF]
Orlov AV +7 more
europepmc +1 more source
A noncanonical role for Jagged1 in endothelial mechanotransduction
The Notch signaling pathway plays a crucial role in regulating endothelial biology. Notch signaling is sensitive to hemodynamic forces and governs mechanically driven cardiovascular development, physiology, and remodeling. This study reveals a non‐canonical role for the Notch ligand Jagged1 in endothelial mechanotransduction.
Freddy Suarez Rodriguez +7 more
wiley +1 more source
Case Report: Biallelic <i>PADI6</i> frameshift variants contribute to preimplantation embryonic lethality. [PDF]
Jiao ST +8 more
europepmc +1 more source
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source
Morphology, Polarization Patterns, Compression, and Entropy Production in Phase-Separating Active Dumbbell Systems. [PDF]
Carenza LM +5 more
europepmc +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Effect of mounting a sound suppressor on distribution and total amount of inorganic gunshot residue on targets. [PDF]
Donghi M +6 more
europepmc +1 more source

