Results 201 to 210 of about 140,313 (357)

Cellular responses in rainbow trout Oncorhynchus mykiss to experimental Anisakis simplex infection. [PDF]

open access: yesParasitol Res
Kumas K   +5 more
europepmc   +1 more source

Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 475-491, January 2026.
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory   +3 more
wiley   +1 more source

Evaluating anaesthetic impacts on rainbow trout mucus biomarkers: towards sustainable aquatic animal welfare. [PDF]

open access: yesFish Physiol Biochem
Tejero M   +6 more
europepmc   +1 more source

Structural insights for enhanced ROS detoxification of eKatE, a recently identified catalase in atypical E. coli

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 196-219, January 2026.
We revealed the crystal structure of eKatE from atypical E. coli. eKatE exhibits a hydrogen‐peroxide‐sensitive major channel, a stabilized dimeric interface, an unusual covalent bond between C392 and Y415, and other distinctive features. These structural features contribute to its enhanced catalase activity compared to KatE in typical E.
Eunhee Koh   +7 more
wiley   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 396-417, January 2026.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury   +16 more
wiley   +1 more source

A meta-analysis of public RNA-Seq data identifies conserved stress responses in rainbow trout. [PDF]

open access: yesBMC Genomics
Bari SM   +5 more
europepmc   +1 more source

Structural insights into how vacuolar sorting receptor recognizes the C‐terminal sorting determinant of a vicilin‐like seed storage protein

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 257-270, January 2026.
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui   +4 more
wiley   +1 more source

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