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Raman Imaging of Small Biomolecules
Annual Review of Biophysics, 2019Imaging techniques greatly facilitate the comprehensive knowledge of biological systems. Although imaging methodology for biomacromolecules such as protein and nucleic acids has been long established, microscopic techniques and contrast mechanisms are relatively limited for small biomolecules, which are equally important participants in biological ...
Yihui Shen, Fanghao Hu, Wei Min
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Research Progress of Raman Spectroscopy and Raman Imaging in Pharmaceutical Analysis
Current Pharmaceutical Design, 2022Abstract: The analytical investigation of the pharmaceutical process monitors the critical process parameters of the drug, beginning from its development until marketing and post-marketing, and appropriate corrective action can be taken to change the pharmaceutical design at any stage of the process.
Jie Ren +5 more
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Themed collection: Biomedical Raman Imaging
The Analyst, 2022Katsumasa Fujita, Paola Borri and Wei Min introduce this Analyst themed issue on Biomedical Raman Imaging.
Katsumasa, Fujita +2 more
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Raman Imaging and Raman Mapping
2009Raman spectroscopy can be used to non-destructively add image contrast in visualizing structures and dynamics in living systems and materials. Image contrast can be derived from any information contained in Raman spectra, including band intensities, positions and widths.
Francis W.L. Esmonde-White +1 more
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Solid State Communications, 2007
Abstract A Raman spectrum of a solid contains information about its vibrational and electronic properties. Collecting spectral data with spatial resolution and encoding it in a 2D plot generates images with information complementary to optical and scanning force imaging. In the case of few-layer graphene the frequency of the G line and especially the
Graf, D. +6 more
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Abstract A Raman spectrum of a solid contains information about its vibrational and electronic properties. Collecting spectral data with spatial resolution and encoding it in a 2D plot generates images with information complementary to optical and scanning force imaging. In the case of few-layer graphene the frequency of the G line and especially the
Graf, D. +6 more
openaire +3 more sources
Stimulated Raman Imaging of Lipids Droplets
2018 20th International Conference on Transparent Optical Networks (ICTON), 2018Lipids are abundant in C-H 2 groups. Thus in their Raman spectrum, the relatively isolated peaks associated with C-H bond vibrational states at 2845 cm-1 provide a unique signature for lipids inside a cell, distinguishing them from other chemical species.
Maria Antonietta Ferrara +6 more
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Live-cell bioorthogonal Raman imaging
Current Opinion in Chemical Biology, 2015Live-cell microscopy demands high specificity, sensitivity, and minimal perturbation to the biomolecules of interest. Meeting all these criteria has been challenging in cellular imaging. Toward this goal, a bioorthogonal Raman imaging method has recently emerged by exploiting small Raman reporters that possess Raman signals that do not overlap with the
Senlian, Hong +3 more
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Coherent Raman Tissue Imaging in the Brain
Cold Spring Harbor Protocols, 2014Imaging in neuroscience has been dramatically impacted by the advent of multiphoton microscopy. Multiphoton-excited fluorescence (MPF) in combination with endogenous fluorophores or labeling by fluorescent molecules has proven to be particularly powerful.
Brian G, Saar +6 more
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Raman imaging of human macular pigments
Optics Letters, 2002We have imaged the spatial distribution of macular carotenoid pigments (MPs) in the human retina, employing Raman spectroscopy. Using excised human eyecups as initial test samples and resonant excitation of the pigment molecules with narrow-bandwidth blue light from a mercury arc lamp, we record Raman images originating from the carbon-carbon double ...
Werner, Gellermann +3 more
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Raman imaging with plasmon surface polaritons
Thin Solid Films, 1993Abstract We report on plasmon surface polariton (PSP) field-enhanced Raman spectroscopy with a two-dimensional detection system that allows microscopic imaging of ultrathin films. The technique offers a means to distinguish between coatings which are optically almost identical films but which have different Raman scattering characteristics.
Nemetz, A., Knobloch, H., Knoll, W.
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