Results 41 to 50 of about 1,626 (189)
CYP2D6 genotype and associated 5-HT<sub>3</sub> receptor antagonist outcomes: A systematic review and meta-analysis. [PDF]
Abstract 5‐hydroxytryptamine‐3 (5‐HT3) receptor antagonists including ondansetron, tropisetron, dolasetron, palonosetron, granisetron, and ramosetron are commonly used to prevent and treat nausea and vomiting. Most of these medications are at least partially metabolized via the highly polymorphic CYP2D6 enzyme, resulting in variations of metabolism ...
Moore C +9 more
europepmc +2 more sources
Postoperative nausea and vomiting (PONV) is extremely distressing and uncomfortable, and is noted frequently in patients who have undergone gynecologic laparoscopic surgery. In this study, we compared the efficacy of a combination of ramosetron plus dexamethasone and ramosetron alone in reducing of PONV after gynecologic laparoscopic surgery.Sixty ...
Dae Seok, Oh +9 more
openaire +2 more sources
Background Arthroscopic rotator cuff repair is a painful procedure, and treatment of emetic events associated with drugs used in the current multimodal pain management remains challenging.
Sang-Uk Lee, Hyo-Jin Lee, Yang-Soo Kim
doaj +1 more source
Patients with quiescent inflammatory bowel disease (IBD) frequently suffer diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms, such as abdominal pain or stool irregularities. Here, we assessed the effect of ramosetron, a serotonin type 3
Mori, Sumire +13 more
core +1 more source
BackgroundPostoperative nausea and vomiting is a distressing complication of surgery, and 5-HT3 receptor antagonists are often prescribed to prevent it.
Ayako Yokoi +3 more
doaj +1 more source
Objective We conducted a systematic literature search and meta-analysis to identify randomized controlled trials (RCTs) comparing the efficacy and safety of ramosetron versus ondansetron for the prevention of postoperative nausea and vomiting (PONV; PON ...
Yiping Li +4 more
doaj +1 more source
Efficacy comparison of ramosetron with ondansetron on preventing nausea and vomiting in high-risk patients following spine surgery with a single bolus of dexamethasone as an adjunct [PDF]
BackgroundDespite the development of a new class of antiemetics, postoperative nausea and vomiting (PONV) still remains a frequent and distressing complication.
Yong Seon Choi +3 more
doaj +1 more source
Palonosetron has superior prophylactic antiemetic efficacy compared with ondansetron or ramosetron in high-risk patients undergoing laparoscopic surgery: a prospective, randomized, double-blinded study [PDF]
BackgroundPostoperative nausea and vomiting (PONV) continues to be a major problem, because PONV is associated with delayed recovery and prolonged hospital stay.
Sung-Hoon Kim +5 more
doaj +1 more source
Control of nausea and vomiting is very important in determining patient compliance with cisplatin chemotherapy. A multicentre, randomized, single-blind study was conducted to compare the tolerability and efficacy of ramosetron with those of granisetron ...
Lee, JA +19 more
core +1 more source
BACKGROUND: The 5-HT(3) receptor antagonists are known to be effective for the treatment of diarrhea-predominant irritable bowel syndrome (IBS), but not widely used yet. The aim of this study was to compare the efficacy and safety of ramosetron, a 5-HT(3)
H. J. Park +27 more
core +2 more sources

