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Biomarker Analysis Beyond Angiogenesis: RAS/RAF Mutation Status, Tumour Sidedness, and Second-Line Ramucirumab Efficacy in Patients With Metastatic Colorectal Carcinoma From RAISE—A Global Phase III Study [PDF]
Annals of Oncology, 2019 Carcinoma colorrectal; Ramucirumab; BRAFCarcinoma colorrectal; Ramucirumab; BRAFColorectal carcinoma; Ramucirumab; BRAFBackground Second-line treatment with ramucirumab+FOLFIRI improved overall survival (OS) versus placebo+FOLFIRI for patients with ...
Josep Tabernero Caturla +2 more
exaly +2 more sources
Ramucirumab for gastric cancer
Expert Review of Gastroenterology & Hepatology, 2014In recent years, various molecular target agents have been investigated for gastric cancer. VEGF is one of the most potent angiogenic factors and is a signaling molecule secreted by many solid tumors. High VEGF expression is one of the characteristic features of gastric carcinomas, thus targeting VEGF is considered a promising strategy for gastric ...
Kohei, Shitara, Atsushi, Ohtsu
openaire +2 more sources