Results 31 to 40 of about 861,631 (286)

Random Allocation in Controlled Clinical Trials: A Review

Journal of Pharmacy & Pharmaceutical Sciences, 2014
PURPOSE: An allocation strategy that allows for chance placement of participants to study groups is crucial to the experimental nature of randomised controlled trials. Following decades of the discovery of randomisation considerable erroneous opinion and
Bolaji Emmanuel Egbewale
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Comparison of Augmented Reality‐Based and Conventional Training Methods for Radiographic Positioning in Second‐Year Radiologic Technology Students in Japan

Journal of Medical Radiation Sciences
Introduction In Japanese training schools for radiologic technologists, improving students' practical skills presents an educational challenge. To address this issue, an augmented reality (AR)‐based visual assistance tool for radiographic positioning ...
Shin Nagamata
doaj   +1 more source

Genotype Performance Estimation in Targeted Production Environments by Using Sparse Genomic Prediction

Plants
In plant breeding, Multi-Environment Trials (METs) evaluate candidate genotypes across various conditions, which is financially costly due to extensive field testing.
Osval A. Montesinos-López, Paolo Vitale, Guillermo Gerard, Leonardo Crespo-Herrera, Carolina Saint Pierre, Abelardo Montesinos-López, José Crossa   +6 more
doaj   +1 more source

A Comparative Crossover Randomized Study of Miller and Macintosh Blade for Laryngoscopic View and Ease of Intubating Conditions in Adults

Archives of Anesthesia and Critical Care, 2021
Background: Although several types of laryngoscope blades of different sizes and shapes are present, Miller (MIL) blade is the most preferable blade among paediatric population. However, there is dearth in the literature regarding the use of these blades
Kadirehally Bheemanna Nalini, Anupama Gopal, Sadasivan Shankar Iyer, Nagaraj Mungasuvalli   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Random allocation software for parallel group randomized trials

BMC Medical Research Methodology, 2004
Background Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output.
Saghaei Mahmood
doaj   +1 more source

Analysis of Human Resource Allocation Model for Tourism Industry Based on Improved BP Neural Network

Journal of Mathematics, 2022
This paper analyzes the deficiencies of human resource allocation in the tourism industry by investigating the human resource allocation in the tourism industry, puts forward corresponding improvement measures and suggestions, and strives to provide ...
Shuo Zhu, Yan Liu
doaj   +1 more source

Asymptotics in randomized urn models

, 2005
This paper studies a very general urn model stimulated by designs in clinical trials, where the number of balls of different types added to the urn at trial n depends on a random outcome directed by the composition at trials 1,2,...,n-1.
Bai, Zhi-Dong, Hu, Feifang
core   +2 more sources