Results 91 to 100 of about 5,099,046 (357)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
On random attractor of semilinear stochastically perturbed wave equation without uniqueness
Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2013 In this paper we investigate the dynamics of solutions of the semilinear wave equation, perturbed by additive white noise, in sense of the random attractor theory. The conditions on the parameters of the problem do not guarantee uniqueness of solution of
G. Iovane +3 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Design and Analysis of a Quadratic Lorenz-like Attractor for Pseudo-Random Number Generation
Cumhuriyet Science JournalThis study introduces and analyzes a novel quadratic Lorenz-like attractor and demonstrates its application as a pseudo-random number generator (PRNG). A theoretical and numerical investigation of the system dynamics is conducted, including equilibrium ...
Bugce Eminaga Tatlicioglu +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Random attractors and nonergodic attractors for diffusions with degeneracies
We consider a diffusion on a bounded domain, assuming that the system is irreducible inside the domain and that the diffusion has varying degree of degeneracy on the domain's boundary. The long-term statistical properties of typical trajectories started inside the domain may be governed by one invariant measure or more than one invariant measure.
Bakhtin, Yuri +2 more
openaire +2 more sources
Existence and upper semicontinuity of random attractors for the 2D stochastic convective Brinkman-Forchheimer equations in bounded domains [PDF]
, 2020 Kush Kinra, Manil T. Mohan
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Electronic Journal of Differential Equations, 2014 This work studies the long-time behavior of two-dimensional micropolar fluid flows perturbed by the generalized time derivative of the infinite dimensional Wiener processes.
Wenqiang Zhao
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