Results 91 to 100 of about 4,980,537 (374)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Random Boolean Networks

open access: yes, 2007
This review explains in a self-contained way the properties of random Boolean networks and their attractors, with a special focus on critical networks.
Drossel, Barbara
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Asymptotic behavior of random coupled Ginzburg–Landau equation driven by colored noise on unbounded domains

open access: yesAdvances in Difference Equations, 2021
In this paper, a random coupled Ginzburg–Landau equation driven by colored noise on unbounded domains is considered, in which the nonlinear term satisfies a local Lipschitz condition.
Zhang Chen, Lingyu Li, Dandan Yang
doaj   +1 more source

Random attractor of stochastic Brusselator system with multiplicative noise

open access: yes, 2015
Asymptotic dynamics of stochastic Brusselator system with multiplicative noise is investigated in this work. The existence of random attractor is proved via the exponential transformation of Ornstein-Uhlenbeck process and some challenging estimates.
J. Tu, Y. You
semanticscholar   +1 more source

The Origin of Non-chaotic Behavior in Identically Driven Systems

open access: yes, 1995
Recently it has been found that different physical systems driven by identical random noise behave exactly identical after a long time. It is also suggested that this is an outcome of finite precision in numerical experiments.
Bracikowski   +18 more
core   +1 more source

Number of attractors in random Boolean networks [PDF]

open access: yesPhysical Review E, 2005
The evaluation of the number of attractors in Kauffman networks by Samuelsson and Troein is generalized to critical networks with one input per node and to networks with two inputs per node and different probability distributions for update functions.
openaire   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Random attractors for stochastic retarded strongly damped wave equations with additive noise on bounded domains

open access: yesOpen Mathematics, 2019
In this paper we study the asymptotic behavior for a class of stochastic retarded strongly damped wave equation with additive noise on a bounded smooth domain in ℝd. We get the existence of the random attractor for the random dynamical systems associated
Jia Xiaoyao, Ding Xiaoquan
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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