Results 81 to 90 of about 46,943 (335)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Random attractors for stochastic retarded strongly damped wave equations with additive noise on bounded domains

open access: yesOpen Mathematics, 2019
In this paper we study the asymptotic behavior for a class of stochastic retarded strongly damped wave equation with additive noise on a bounded smooth domain in ℝd. We get the existence of the random attractor for the random dynamical systems associated
Jia Xiaoyao, Ding Xiaoquan
doaj   +1 more source

The random case of Conley's theorem: III. Random semiflow case and Morse decomposition

open access: yes, 2007
In the first part of this paper, we generalize the results of the author \cite{Liu,Liu2} from the random flow case to the random semiflow case, i.e. we obtain Conley decomposition theorem for infinite dimensional random dynamical systems.
Arnold L   +25 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Asymptotic Dynamics of a Class of Coupled Oscillators Driven by White Noises

open access: yes, 2012
This paper is devoted to the study of the asymptotic dynamics of a class of coupled second order oscillators driven by white noises. It is shown that any system of such coupled oscillators with positive damping and coupling coefficients possesses a ...
Shen, Wenxian   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Upper Semicontinuity of Random Attractors for Nonautonomous Stochastic Reversible Selkov System with Multiplicative Noise

open access: yesAdvances in Mathematical Physics, 2019
In this paper, the existence of random attractors for nonautonomous stochastic reversible Selkov system with multiplicative noise has been proved through Ornstein-Uhlenbeck transformation.
Chunxiao Guo, Yanfeng Guo, Xiaohan Li
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Improving Quantum Approximate Optimization by Noise-Directed Adaptive Remapping [PDF]

open access: yesQuantum
We present Noise-Directed Adaptive Remapping (NDAR), a heuristic algorithm for approximately solving binary optimization problems by leveraging certain types of noise.
Filip B. Maciejewski   +3 more
doaj   +1 more source

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