Results 131 to 140 of about 23,664,335 (320)

Understanding correlates of child stunting in Ethiopia using generalized linear mixed models

BMC Public Health, 2019
Background Stunting is an indicator of the devastating result of malnutrition in early childhood. The effects of childhood stunting are irreparable physical and cognitive harm.
Kasahun Takele, Temesgen Zewotir, Denis Ndanguza   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Random Effect Transformation for Three Regularity Classes

Mathematics
We continue the analysis of the influence of the random effect transformation on the regularity of distribution functions. The paper considers three regularity classes: heavy-tailed distributions, distributions with consistently varying tails, and ...
Jonas Šiaulys, Sylwia Lewkiewicz, Remigijus Leipus   +2 more
doaj   +1 more source

Random effect misspecification in stepped wedge designs. [PDF]

Clin Trials, 2022
Voldal EC, Xia F, Kenny A, Heagerty PJ, Hughes JP.   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Foreign direct investment legislation and economic growth in Western Balkan countries: a panel analysis

Technological and Economic Development of Economy
Foreign direct investment (FDI) legislation plays a crucial role in fetching foreign investments. The objective of this study is to measure the impact of FDI on the Western Balkans countries (WBCs) and interpret the FDI law in the said countries.
Xhemazie Ibraimi, Besime Fekri Ziberi, Nawaz Ahmad, Jolita Vveinhardt   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Comment on the selection of the fixed or random effect model in a study. [PDF]

Transl Pediatr, 2022
Sun Y, Guo Y, Wu J.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The R Package geepack for Generalized Estimating Equations

Journal of Statistical Software, 2005
This paper describes the core features of the R package geepack, which implements the generalized estimating equations (GEE) approach for fitting marginal generalized linear models to clustered data.
Ulrich Halekoh, Søren Højsgaard, Jun Yan   +2 more
doaj