Results 81 to 90 of about 23,664,335 (320)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Metaan: Random-effects Meta-analysis [PDF]
This article describes the new meta-analysis command metaan, which can be used to perform fixed- or random-effects meta-analysis. Besides the standard DerSimonian and Laird approach, metaan offers a wide choice of available models: maximum likelihood, profile likelihood, restricted maximum likelihood, and a permutation model.
Kontopantelis, Evangelos, Reeves, David
openaire +2 more sources
Effect of Dependent Scattering on Light Absorption in Highly Scattering Random Media
The approximate nature of radiative transfer equation (RTE) leads to a bunch of considerations on the effect of "dependent scattering" in random media, especially particulate media composed of discrete scatterers, in the last a few decades, which usually
Wang, B. X., Zhao, C. Y.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Effect of Random Parameter Switching on Commensurate Fractional Order Chaotic Systems
The paper explores the effect of random parameter switching in a fractional order (FO) unified chaotic system which captures the dynamics of three popular sub-classes of chaotic systems i.e. Lorenz, Lu and Chen's family of attractors.
Das, Saptarshi +2 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Human Development and Its Effects on Economic Growth and Development
The focus of the current study is to empirically examine the impact of Human Development on Economic Growth and Development in African countries, between 1990 and 2015.
Michael Appiah +2 more
doaj +1 more source
Disorder effects at a nematic quantum critical point in d-wave cuprate superconductor
A d-wave high temperature cuprate superconductor exhibits a nematic ordering transition at zero temperature. Near the quantum critical point, the coupling between gapless nodal quasiparticles and nematic order parameter fluctuation can result in unusual ...
Kleinert, Hagen +2 more
core +1 more source

