Results 131 to 140 of about 3,837,977 (302)
, 2014 Experimental investigations into the dynamic response of structures with material or geometrical random fields usually depend upon an initial characterization of this variability, with very little control over the statistics at its early manufacturing ...
Ferguson, N.S. +4 more
core +1 more source
Dynamic Analysis of a Vehicle–Bridge System Under Excitation of Random Road Irregularities
BuildingsThis paper presents a comprehensive study of the dynamic response analysis of vehicle–bridge coupled systems, with detailed simulation methods for the vehicles, bridges, and wheel–road coupling relationships.
Yue Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Baozha yu ChongjiIn order to study the blast performance of ultra-high performance concrete (UHPC) panels under intermedium-to-far-field explosion loading, a series of field blast tests were conducted to systematically analyze the influence of scaled blast distances on ...
Shilang XU +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Random walks on Galton-Watson trees with infinite variance offspring distribution conditioned to survive [PDF]
, 2008 We establish a variety of properties of the discrete time simple random walk on a Galton-Watson tree conditioned to survive when the offspring distribution, Z say, is in the domain of attraction of a stable law with index alpha is an element of (1,2]. In
Croydon, David A., Kumagai, Takashi
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Discrete limit theorems for general Dirichlet series. III
Open Mathematics, 2004 Laurinčikas A., Macaitienė R.
doaj +1 more source
Random Forests for Multiclass Classification: Random
, 2008 —Several supervised learning algorithms are suited to classify instances into a multiclass value space. MultiNomial Logit (MNL) is recognized as a robust classifier and is commonly applied within the CRM (Customer Relationship Management) domain ...
Multinomial Logit +1 more
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source