Results 91 to 100 of about 15,642,613 (349)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Optimal random sampling designs in random field sampling [PDF]
, 2003 A Horvitz-Thompson predictor is proposed for spatial sampling when the characteristic of interest is modeled as a random field. Optimal sampling designs are deduced under this context.
Rodríguez, José E., Ávila, Fernando
core
Stereological 3D modeling of nano-scale catalyst particles using TEM projections
Machine Learning: Science and TechnologyCatalysis, particularly heterogeneous catalysis, is crucial in the chemical industry and energy storage. Approximately 80% of all chemical products produced by heterogeneous catalysis are produced by solid catalysts, which are essential for the synthesis
Lukas Fuchs +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Conformal field theories on random surfaces and the non-critical string [PDF]
, 1997 Recently, it has become increasingly clear that boundaries play a significant role in the understanding of the non-perturbative phase of the dynamics of strings.
Neves, Rui Gomes Mendona
core
On Some Methods in Safety Evaluation in Geotechnics
Studia Geotechnica et Mechanica, 2015 The paper demonstrates how the reliability methods can be utilised in order to evaluate safety in geotechnics. Special attention is paid to the so-called reliability based design that can play a useful and complementary role to Eurocode 7.
Puła Wojciech, Zaskórski Łukasz
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
REVIEW OF RECENT RESULTS ON EXCURSION SET MODELS
Image Analysis and Stereology, 2011 Many images consist of two or more "phases", where a phase is a collection of homogeneous zones. For example, the phases may represent the presence of different sulphides in an ore sample.
Richard J Wilson, David J Nott
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source