Results 71 to 80 of about 267,735 (315)
Edges generation by random graph erdos-royi methods was needed high computation, it’s caused low performance. In fact, edge generation was used frequently with many nodes.
Zainal Abidin, Agus Zainal Arifin
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Revised chapter for new edition of book "The Mathematics of Paul Erd\H{o}s"
openaire +2 more sources
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Random Regular Graph States Are Complex at Almost Any Depth
Graph states are fundamental objects in the theory of quantum information due to their simple classical description and rich entanglement structure. They are also intimately related to instantaneous quantum polynomial-time (IQP) circuits, which have ...
Soumik Ghosh +2 more
doaj +1 more source
Subgraphs of random graphs [PDF]
Let Δ ⊆ [ ω ] 2 \Delta \subseteq {[\omega ]^2} be an undirected graph on ω \omega , and let u ∈ [ 0 , 1 ] u \in [0,\,1] . Following P. Erdös and A.
Fremlin, David H., Talagrand, Michel
openaire +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
On the Edge-Connectivity of an Uncertain Random Graph
Connectivity is one of the most important concepts in graph theory. When graph theory is applied to complex systems with indeterminate factors, uncertainty and randomness are two basic types of indeterminacy.
Hao Li, Hui Zhang
doaj +1 more source
Treewidth of Erdős–Rényi random graphs, random intersection graphs, and scale-free random graphs
We prove that the treewidth of an Erd s-R nyi random graph $\rg{n, m}$ is, with high probability, greater than $ n$ for some constant $ > 0$ if the edge/vertex ratio $\frac{m}{n}$ is greater than 1.073. Our lower bound $\frac{m}{n} > 1.073$ improves the only previously-known lower bound.
openaire +2 more sources

