Results 71 to 80 of about 1,095,825 (329)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Random subgraphs of certain graph powers

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
We determine the limiting probability that a random subgraph of the Cartesian power Kan or of Ka,an is connected.
Lane Clark
doaj   +1 more source

On the Validity of Neural Mass Models

open access: yesFrontiers in Computational Neuroscience, 2021
Modeling the dynamics of neural masses is a common approach in the study of neural populations. Various models have been proven useful to describe a plenitude of empirical observations including self-sustained local oscillations and patterns of distant ...
Nicolás Deschle   +6 more
doaj   +1 more source

The average number of distinct sites visited by a random walker on random graphs

open access: yes, 2015
We study the linear large $n$ behavior of the average number of distinct sites $S(n)$ visited by a random walker after $n$ steps on a large random graph. An expression for the graph topology dependent prefactor $B$ in $S(n) = Bn$ is proposed.
De Bacco, Caterina   +2 more
core   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Random graphs on surfaces

open access: yesJournal of Combinatorial Theory, Series B, 2008
Counting labelled planar graphs, and typical properties of random labelled planar graphs, have received much attention recently. We start the process here of extending these investigations to graphs embeddable on any fixed surface S. In particular we show that the labelled graphs embeddable on S have the same growth constant as for planar graphs ...
openaire   +4 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Estrada Index and Laplacian Estrada Index of Random Interdependent Graphs

open access: yesMathematics, 2020
Let G be a simple graph of order n. The Estrada index and Laplacian Estrada index of G are defined by E E ( G ) = ∑ i = 1 n e λ i ( A ( G ) ) and L E E ( G ) = ∑ i = 1 n e λ i ( L ( G ) ) , where { λ i
Yilun Shang
doaj   +1 more source

k-connectivity of Random Graphs and Random Geometric Graphs in Node Fault Model

open access: yes, 2018
k-connectivity of random graphs is a fundamental property indicating reliability of multi-hop wireless sensor networks (WSN). WSNs comprising of sensor nodes with limited power resources are modeled by random graphs with unreliable nodes, which is known ...
bollobás   +7 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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