Results 71 to 80 of about 276,499 (268)
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
On the Edge-Connectivity of an Uncertain Random Graph
Connectivity is one of the most important concepts in graph theory. When graph theory is applied to complex systems with indeterminate factors, uncertainty and randomness are two basic types of indeterminacy.
Hao Li, Hui Zhang
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Random Regular Graph States Are Complex at Almost Any Depth
Graph states are fundamental objects in the theory of quantum information due to their simple classical description and rich entanglement structure. They are also intimately related to instantaneous quantum polynomial-time (IQP) circuits, which have ...
Soumik Ghosh +2 more
doaj +1 more source
A Comprehensive Approach to Synthetic Distribution Grid Generation: Erdős–Rényi to Barabási-Albert [PDF]
In this extended study, the focus is on advancing the generation of synthetic distribution grids (SDGs) through the introduction of a new algorithm based on the Barabási-Albert random graph model.
Mohammad Shahraeini
doaj +1 more source
Non symmetric random walk on infinite graph [PDF]
We investigate properties of a non symmetric Markov's chain on an infinite graph. We show the connection with matrix valued random walk polynomials which satisfy the orthogonality formula with respect to non a symmetric matrix valued measure.
Marcin J. Zygmunt
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
On the Reliability of Wireless Sensor Networks with Multiple Sinks
The convergence of heterogeneous wireless sensor networks provides many benefits, including increased coverage, flexible load balancing capabilities, more efficient use of network resources, and the provision of additional data by different types of ...
Vladimir Shakhov, Denis Migov
doaj +1 more source

