Results 71 to 80 of about 2,603,262 (299)

Asymptotics of m-Cliques in a Sparse Inhomogeneous Random Graph

open access: yesJournal of Mathematics, 2022
One of the classical questions in random graph theory is to understand the asymptotics of subgraph counts. In inhomogeneous random graph, this question has not been well studied. In this study, we investigate the asymptotic distribution of m-cliques in a
Xiaofeng Zhao
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

A Comprehensive Approach to Synthetic Distribution Grid Generation: Erdős–Rényi to Barabási-Albert [PDF]

open access: yesAUT Journal of Electrical Engineering
In this extended study, the focus is on advancing the generation of synthetic distribution grids (SDGs) through the introduction of a new algorithm based on the Barabási-Albert random graph model.
Mohammad Shahraeini
doaj   +1 more source

Central limit theorem for the principal eigenvalue and eigenvector of Chung–Lu random graphs

open access: yesJournal of Physics: Complexity, 2023
A Chung–Lu random graph is an inhomogeneous Erdős–Rényi random graph in which vertices are assigned average degrees, and pairs of vertices are connected by an edge with a probability that is proportional to the product of their average degrees ...
Pierfrancesco Dionigi   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

On the Edge-Connectivity of an Uncertain Random Graph

open access: yesIEEE Access, 2020
Connectivity is one of the most important concepts in graph theory. When graph theory is applied to complex systems with indeterminate factors, uncertainty and randomness are two basic types of indeterminacy.
Hao Li, Hui Zhang
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

On the Reliability of Wireless Sensor Networks with Multiple Sinks

open access: yesSensors
The convergence of heterogeneous wireless sensor networks provides many benefits, including increased coverage, flexible load balancing capabilities, more efficient use of network resources, and the provision of additional data by different types of ...
Vladimir Shakhov, Denis Migov
doaj   +1 more source

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