Results 61 to 70 of about 180,895 (263)
Revised chapter for new edition of book "The Mathematics of Paul Erd\H{o}s"
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Random graphs, models and generators of scale-free graphs
In this paper various models of random graphs describing real networks arising in different research fields: biology, computer science, engineering, sociology are considered. Particular attention is paid to models describing social networks.
M. M. Bernovskiy, N. N. Kuzyurin
doaj
Fast Generation of Sparse Random Kernel Graphs. [PDF]
The development of kernel-based inhomogeneous random graphs has provided models that are flexible enough to capture many observed characteristics of real networks, and that are also mathematically tractable.
Aric Hagberg, Nathan Lemons
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Largest Component in Critical Random Intersection Graphs
In this paper, through the coupling and martingale method, we prove the order of the largest component in some critical random intersection graphs is n23$n^{{2 \over 3}}$ with high probability and the width of scaling window around the critical ...
Wang Bin, Wang Longmin, Xiang Kainan
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Universal distance domination in random graphs
Given a graph G=(V,E)D⊆VV∖DDGγ(G)GkDDdDk uk(G):= min {d:∀ D⊆V with |D|≥d,D is a kdd set in G}.kuk(G)γ(G)=u1(G)ukkkkH ...
Gábor Bacsó +2 more
doaj +1 more source

