Results 61 to 70 of about 21,293 (257)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

The Origin of Threshold Reduction in Random Lasers Based on MoS₂/Au NPs: Charge Transfer

Photonics
Random lasers have attracted much attention in recent years owing to their advantages of a simple fabrication process, low processing cost, and material flexibility for any lasing wavelengths.
Yanyan Huo, Ke Sun, Yuqian Zhang, Weihao Liu, Junkun Wang, Yuan Wan, Lina Zhao, Tingyin Ning, Zhen Li, Yingying Ren   +9 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

ZnO nanorod array random lasers fabricated by a laser-induced hydrothermal synthesis

New Journal of Physics, 2016
We demonstrate random lasing in ZnO nanorod array (NRA) structures fabricated by a laser-induced hydrothermal growth, which would make it possible to control structural parameters, such as diameter, length, density and so on, by adjusting the laser ...
Hideki Fujiwara, Takemasa Suzuki, Ryo Niyuki, Keiji Sasaki   +3 more
doaj   +1 more source

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

Advanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo, Shuo Qu, Shiming Gao, Xu Song   +3 more
wiley   +1 more source

Full Bandwidth Time-Domain Intensity Statistical Characteristics of Raman Random Fiber Laser Based on a Temporal Dynamics Controllable Pump

Photonics
The temporal dynamics and statistical characteristics of Raman random fiber lasers are of great significance for studying their physical properties and applications.
Zhitao Leng, Mengqiu Fan, Han Wu
doaj   +1 more source

Identifying the Contribution of Carrier Shot Noise and Random Carrier Recombination to Excess Frequency Noise in Tunable Lasers

Photonics, 2019
Tunable lasers are necessary devices for modern-day telecommunications and sensing systems. Tunable lasers based on altering the refractive index of the tuning sections of distributed Bragg reflectors (DBR) by varying the injected electrical current show
Sean O’Duill, Yi Lin, Liam Barry
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source