Results 101 to 110 of about 546,736 (277)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Accelerating Content Delivery via Efficient Resource Allocation for Network Coding Aided D2D Communications

open access: yesIEEE Access, 2019
Device-to-device (D2D) communication is one of the emerging paradigms in 5G networks to facilitate ever-increasing demands for local area services. For content delivery, direct transmission via D2D communications among proximity nodes and cooperative ...
Xuefeng Xiao   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

DNAE-GAN: Noise-free acoustic signal generator by integrating autoencoder and generative adversarial network

open access: yesInternational Journal of Distributed Sensor Networks, 2020
Linear predictive coding is an extremely effective voice generation method that operates through simple process. However, linear predictive coding–generated voices have limited variations and exhibit excessive noise.
Ping-Huan Kuo, Ssu-Ting Lin, Jun Hu
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Systematic-RLNC Based Secure and QoS Centric Routing Scheme for WSNs

open access: yesJournal of Telecommunications and Information Technology, 2019
In this paper a highly robust and efficient systematic-random linear network coding (S-RLNC) routing scheme is proposed. Unlike classic security systems, the proposed S-RLNC transmission model incorporates an advanced pre-coding and interleaving concept ...
Ajaykumar Notom   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Application Layer Systematic Network Coding for Sliced H.264/AVC Video Streaming

open access: yesAdvances in Multimedia, 2012
Application Layer Forward Error Correction (AL-FEC) with rateless codes can be applied to protect the video data over lossy channels. Expanding Window Random Linear Codes (EW RLCs) are a flexible unequal error protection fountain coding scheme which can ...
Sajid Nazir   +3 more
doaj   +1 more source

Random linear fountain code with improved decoding success probability [PDF]

open access: yes2016 22nd Asia-Pacific Conference on Communications (APCC), 2016
This paper appears in: Communications (APCC), 2016 22nd Asia-Pacific Conference ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy