Results 61 to 70 of about 797,910 (276)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Level Compressibility of Certain Random Unitary Matrices

Entropy, 2022
The value of spectral form factor at the origin, called level compressibility, is an important characteristic of random spectra. The paper is devoted to analytical calculations of this quantity for different random unitary matrices describing models with
Eugene Bogomolny
doaj   +1 more source

CMV matrices in random matrix theory and integrable systems: a survey

, 2005
We present a survey of recent results concerning a remarkable class of unitary matrices, the CMV matrices. We are particularly interested in the role they play in the theory of random matrices and integrable systems.
Ammar G S, Babelon O, Cantero M J Moral L Velázquez L, Deift P, Dyson F, Faybusovich L, Fermi E, Forrester P J Rains E M, Gekhtman M, Gelfand I M, Geronimus Ya L, Geronimus Ya L, Irina Nenciu, Killip R Nenciu I, Li L-C, Moser J, Olshanetsky M A, Simon B, Simon B, Szegő G, Thiele C Tao T, Toda M   +21 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Perturbations of diagonal matrices by band random matrices [PDF]

, 2011
We exhibit an explicit formula for the spectral density of a (large) random matrix which is a diagonal matrix whose spectral density converges, perturbated by the addition of a symmetric matrix with Gaussian entries and a given (small) limiting variance ...
Benaych-Georges, Florent, Enriquez, Nathanaël   +1 more
core   +3 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Generalized Ensemble of Random Matrices [PDF]

Physical Review Letters, 1994
9 ...
Moshe, Moshe, Neuberger, Herbert, Shapiro, Boris   +2 more
openaire   +3 more sources

2D Gravity and Random Matrices

, 1994
We review recent progress in 2D gravity coupled to ...
't Hooft, Alvarez-Gaumé, Ambjørn, Aoki, Bachas, Bachas, Banks, Belavin, Bershadsky, Bershadsky, Bershadsky, Bessis, Boulatov, Boulatov, Boulatov, Boutroux, Brezin, Brezin, Brézin, Brézin, Brézin, Brézin, Brézin, Crnković, D'Hoker, David, David, David, David, David, David, David, Di Francesco, Di Francesco, Di Francesco, Dijkgraaf, Dijkgraaf, Dijkgraaf, Dijkgraaf, Dijkgraaf, Distler, Dotsenko, Douglas, Douglas, Douglas, Douglas, Drinfeld, Eguchi, Eynard, Eynard, Feigin, Francesco, Francesco, Francesco, Francesco, Fröhlich, Fukazawa, Fukuma, Gaudin, Gerasimov, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Goulian, Gross, Gross, Gross, Harish, Harris, Hille, Itzykson, Itzykson, J. Zinn-Justin, Karliner, Karliner, Kazakov, Kazakov, Kazakov, Kazakov, Kharchev, Klebanov, Knizhnik, Kontsevich, Kontsevich, Kostov, Kostov, Kostov, Kreuzer, Kunitomo, Kutasov, Kutasov, Li, Makeenko, Marinari, Marshakov, Marshakov, Martinec, Moore, Moore, P. Ginsparg, P.Di Francesco, Polyakov, Polyakov, Sakai, Seiberg, Seiberg, Selberg, Shenker, Staudacher, Tada, Weingarten, Witten, Witten, Witten, Zamolodchikov, Zinn-Justin   +118 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source