Results 61 to 70 of about 167,620 (262)
Level Compressibility of Certain Random Unitary Matrices
Entropy, 2022 The value of spectral form factor at the origin, called level compressibility, is an important characteristic of random spectra. The paper is devoted to analytical calculations of this quantity for different random unitary matrices describing models with
Eugene Bogomolny
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Proceedings of the International Congress of Mathematicians (ICM 2018), 2019 We survey recent mathematical results about the spectrum of random band matrices. We start by exposing the Erd{\H o}s-Schlein-Yau dynamic approach, its application to Wigner matrices, and extension to other mean-field models. We then introduce random band matrices and the problem of their Anderson transition.
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On the Singularity of Random Combinatorial Matrices [PDF]
SIAM Journal on Discrete Mathematics, 2013 It is shown that a random $(0,1)$ matrix whose rows are independent random vectors of exactly $n/2$ zero components is non-singular with probability $1-O(n^{-C})$ for any $C>0$. The proof uses a non-standard inverse-type Littlewood-Offord result.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Realistic Many-Body Quantum Systems vs. Full Random Matrices: Static and Dynamical Properties
Entropy, 2016 We study the static and dynamical properties of isolated many-body quantum systems and compare them with the results for full random matrices. In doing so, we link concepts from quantum information theory with those from quantum chaos.
Eduardo Jonathan Torres-Herrera +3 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source