Results 51 to 60 of about 1,877,864 (293)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Soil moisture inversion of oasis saline soil based on early-time signals of multi-frequency GPR

open access: yes地球与行星物理论评
Oasis agriculture in arid regions persistently faces dual challenges of water scarcity and secondary soil salinization, making accurate acquisition of spatiotemporal soil moisture distribution characteristics critical for sustaining agricultural ...
Tianbao Huang   +7 more
doaj   +1 more source

On large deviation regimes for random media models

open access: yes, 2009
The focus of this article is on the different behavior of large deviations of random subadditive functionals above the mean versus large deviations below the mean in two random media models.
Cranston, M.   +2 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Propagation and organization in lattice random media

open access: yes, 1999
We show that a signal can propagate in a particular direction through a model random medium regardless of the precise state of the medium. As a prototype, we consider a point particle moving on a one-dimensional lattice whose sites are occupied by ...
Boon, Jean Pierre   +3 more
core   +1 more source

Free energy fluctuations for directed polymers in random media in 1+1 dimension [PDF]

open access: yes, 2012
We consider two models for directed polymers in space-time independent random media (the O'Connell-Yor semi-discrete directed polymer and the continuum directed random polymer) at positive temperature and prove their KPZ universality via asymptotic ...
Borodin, Alexei   +2 more
core   +4 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Statistics of Extreme Waves in Random Media

open access: yes, 2013
Waves traveling through random media exhibit random focusing that leads to extremely high wave intensities even in the absence of nonlinearities. Although such extreme events are present in a wide variety of physical systems and the statistics of the ...
Fleischmann, Ragnar   +2 more
core   +1 more source

Pulse propagation in time dependent randomly layered media [PDF]

open access: yes, 2016
We study cumulative scattering effects on wave front propagation in time dependent randomly layered media. It is well known that the wave front has a deterministic characterization in time independent media, aside from a small random shift in the travel ...
Borcea, Liliana, Solna, Knut
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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