Results 101 to 110 of about 12,894,590 (275)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
TRIM: AI Guided Random Number Generation for Resource-Constrained IoT Systems
IEEE AccessRandom numbers often serve as the backbone for many security solutions in diverse domains such as cryptography, side channel leakage prevention, and moving target defense. However, generating true random numbers requires a physical source of entropy (e.g.
Tasneem Suha +5 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Spin-based true random number generation enabled by voltage-amplified quantum fluctuations
New Journal of PhysicsWe investigate spin quantum-fluctuation effects that originate from the Heisenberg uncertainty principle during the dynamical cycle of disentanglement, entanglement, and re-disentanglement between itinerant electrons and localized magnetic moments ...
Jie Zheng +8 more
doaj +1 more source
High-Speed and Scalable Quantum Random Number Generation Using InGaN Micro-LEDs
IEEE Photonics JournalThis paper presents a high-speed and scalable quantum random number generator (QRNG) based on InGaN micro-LED arrays. While traditional QRNG systems face limitations in data rate and integration complexity, our approach leverages the intrinsic quantum ...
Fu-He Hsiao +8 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Quantum random number generation using an on-chip nanowire plasmonic waveguide
New Journal of PhysicsQuantum random number generators employ the inherent randomness of quantum mechanics to generate truly unpredictable random numbers, which are essential in cryptographic applications.
C Strydom +3 more
doaj +1 more source
Random Number Generation Based on Heterogeneous Entropy Sources Fusion in Multi-Sensor Networks. [PDF]
Sensors (Basel), 2023 Zhang J, Wu M.
europepmc +1 more source
, 2017 Low-energy random number generation is critical for many emerging computing schemes proposed to complement or replace von Neumann architectures. However, current random number generators are always associated with an energy cost that is prohibitive for ...
Grollier, Julie +25 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source