Results 191 to 200 of about 71,987 (254)

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali   +14 more
wiley   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source
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Random-number generators

Computers and Biomedical Research, 1968
Abstract A commonly used uniform random-number generator is examined in light of a genetic-simulation problem. Although this generator is often useful, it proves defective in this case. The author suggests that any proposed generator be checked for the properties needed by the simulation problem at hand.
openaire   +2 more sources

Random Number Generation [PDF]

open access: possible, 2011
The fields of probability and statistics are built over the abstract concepts of probability space and random variable. This has given rise to elegant and powerful mathematical theory, but exact implementation of these concepts on conventional computers seems impossible.
openaire   +2 more sources

Random number generators are chaotic

ACM SIGPLAN Notices, 1989
We observe that pseudo-random number generators, familiar to all programmers, are examples of deterministic chaotic dynamical systems. We discuss the implications of this finding and compare computer generation of pseudo-random numbers to the theoretical ideal of a (noncomputable) random sequence.
Charles Herring, Julian I. Palmore
openaire   +1 more source

Random number generators

Preprints of papers presented at the 14th national meeting of the Association for Computing Machinery on - ACM '59, 1959
One requirement common to all Monte Carlo computer simulations is an abundant and automatic supply of random numbers. For most purposes it generally suffices to draw this supply from the uniform distribution in the unit interval. The mathematical tricks used to convert these samplings to samplings from other distributions are well-known.
openaire   +1 more source

Uniform Random Number Generators

Journal of the ACM, 1965
Abstract : This paper discusses the testing of methods for generating uniform numbers in a computer--the commonly used multiplicative and mixed congruential generators as well as two methods. Tests proposed here are more stringent than those usually applied, because the usual tests for randomness have passed several of the commonly used pprocedures ...
M. Donald MacLaren, George Marsaglia
openaire   +1 more source

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