Results 71 to 80 of about 77,348 (299)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Measurement-Device-Independent Quantum Random-Number Generator With Source Flaws
IEEE Photonics Journal, 2023 The measurement-device-independent quantum random number generator (MDI-QRNG) can resist all security loopholes on measurement devices, and it thus seems very promising in practical implementations.
Tao Wu +4 more
doaj +1 more source
On the Construction of Random Number Generators and Random Function Generators [PDF]
, 1988 Blum, Micali (1982), Yao (1982), Goldreich, Goldwasser and Micali (1984), and Luby, Rackoff (1986) have constructed random number generators, random function generators and random permutation generators that are perfect if certain complexity assumptions hold.
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Binarizations in random number generation
2016 IEEE International Symposium on Information Theory (ISIT), 2016 Extracting procedures produce unbiased random bits from biased coin flips. Binarizations take inputs from an m-faced dice and produce bit sequences to be fed into a (binary) extracting procedure to obtain random bits, and this can be done in an entropy-preserving manner, without loss of information. Such a procedure has been proposed by Zhou and Bruck [
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A Hardware Random Number Generator [PDF]
, 2003 Some of the desirable properties a cryptographic random number generator should have are lack of bias, bit independence, unpredictiability and nonrepeatability. In this paper, we discuss how a hardware random number generator formed from simple components can provide these properties. The components include two state machines with different structures,
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
AIP Advances, 2020 The need for hardware random number generators (HRNGs) that can be integrated in a silicon (Si) complementary-metal–oxide–semiconductor (CMOS) platform has become increasingly important in the era of the Internet-of-Things (IoT).
Kouta Ibukuro +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source