Limitations of the refolding pipeline for de novo protein design
Abstract With the emergence of powerful deep learning‐based tools, computational protein design has become a widely accessible technique. Nowadays, it is possible to perform both sequence and structure design in a matter of minutes, making the technology attractive to the broader scientific community. In protein design campaigns, one of the most common
Kerlen T. Korbeld +2 more
wiley +1 more source
Variable Selection in Ultra-high Dimensional Feature Space for the Cox Model with Interval-Censored Data. [PDF]
Pak D, Zhang J, Wu D, Weng H, Li C.
europepmc +1 more source
Child Brides in Africa: A Narrative Review on Effects, Gaps, and Interventions
Child marriage, defined as union before age 18, affects millions of girls across sub‐Saharan Africa, with Niger, Chad, Mali, Guinea, and Nigeria recording prevalence rates of 40–76%. This review synthesises evidence on the prevalence, sociocultural and economic drivers, and health, psychological, and social consequences of child marriage in Africa ...
Olaoye Damilola Quazeem +6 more
wiley +1 more source
Assessing Treatment Effects in Observational Data With Missing Confounders: A Comparative Study of Practical Doubly-Robust and Traditional Missing Data Methods. [PDF]
Williamson BD +15 more
europepmc +1 more source
Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP‐Mediated Mechanotransduction
International Journal of Dermatology, Volume 65, Issue 7, Page 1553-1556, July 2026.
Jimyung Seo +5 more
wiley +1 more source
Variable Selection for Illness‐Death Processes Under Dual Observation Schemes
ABSTRACT The classical illness‐death process offers a useful framework for studying the progression of chronic disease while jointly modeling death. In many settings the time of disease progression is not observed directly, but progression status is recorded at intermittent assessment times.
Xianwei Li, Liqun Diao, Richard J. Cook
wiley +1 more source
A dynamic policy-aware conditional proxy re-encryption system for fine-grained access control in IoT pub/sub systems. [PDF]
Lin S, Ke N, Jun Ru H, Cui L.
europepmc +1 more source
ABSTRACT Depicting patient transitions among multiple clinical states is a common objective in health services and epidemiological research. Multistate models (MSM) are the primary analytical approach used in such studies. Although the structure of an MSM is typically determined by the research questions of a specific application, models are typically ...
Jason Mao, Yang Li, Wanzhu Tu
wiley +1 more source
Prediction Pipeline Selection for Incomplete Clinical Data via Missingness Fingerprints and Instance Augmentation. [PDF]
Li R, Shen Z, Wu C, Li J, Tian Y.
europepmc +1 more source
Finding Minimum‐Cost Explanations for Predictions Made by Tree Ensembles
ABSTRACT The ability to reliably explain why a machine learning model arrives at a particular prediction is crucial when used as decision support by human operators of critical systems. The provided explanations must be provably correct, and preferably without redundant information, called minimal explanations.
John Törnblom +2 more
wiley +1 more source

