Results 71 to 80 of about 258,206 (308)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Growth and structure of a young Aleppo pine planted forest after thinning for diversification and wildfire prevention

open access: yesForest Systems, 2013
Aim of study: In the Mediterranean, low timber-production forests are frequently thinned to promote biodiversity and reduce wildfire risk, but few studies in the region have addressed such goals.
J. Ruiz-Mirazo, J. L. Gonzalez-Rebollar
doaj   +1 more source

Random walks on trees

open access: yesDiscrete Mathematics, 1980
AbstractThe classical gambler's ruin problem, i.e., a random walk along a line may be viewed graph theoretically as a random walk along a path with the endpoints as absorbing states. This paper is an investigation of the natural generalization of this problem to that of a particle walking randomly on a tree with the endpoints as absorbing barriers ...
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Severity Analysis of Macular Edema using Random Tree Classifier

open access: yes, 2018
Macular edema ensues when there is abnormal pile-up of fluid and results in swelling of the macula part of the retina. It is commonly associated with diabetes. It can be diagnosed by identifying exudates in the retinal images.
Venugopal K R, Deepthi K Prasad, Vibha L
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Limits of random trees [PDF]

open access: yesActa Mathematica Hungarica, 2013
Local convergence of bounded degree graphs was introduced by Benjamini and Schramm. This result was extended further by Lyons to bounded average degree graphs. In this paper, we study the convergence of a random tree sequence where the probability of a given tree is proportional to $\prod_{v_i\in V(T)}d(v_i)!$.
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Research on Risk Detection of Autonomous Vehicle Based on Rapidly-Exploring Random Tree [PDF]

open access: yes, 2023
There is no doubt that the autonomous vehicle is an important developing direction of the auto industry, and, thus, more and more scholars are paying attention to doing more research in this field. Since path planning plays a key role in the operation of
Tan, Min Keng   +9 more
core   +1 more source

Effect of Hyperparameter Tuning Using Random Search on Tree-Based Classification Algorithm for Software Defect Prediction

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems)
The field of information technology requires software, which has significant issues. Quality and reliability improvement needs damage prediction. Tree-based algorithms like Random Forest, Deep Forest, and Decision Tree offer potential in this domain ...
Muhammad Hevny Rizky   +4 more
doaj   +1 more source

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