Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
On the Lebesgue measure of one generalised set of subsums of geometric series
Математичні СтудіїIn the present paper, we study a set that can be treated as a generalised set of subsums for a geometric series. This object was discovered independently in various mathematical aspects.
O. P. Makarchuk, D. M. Karvatskyi
doaj +1 more source
On The Quotient of a Centralized and a Non-centralized Complex Gaussian Random Variable. [PDF]
J Res Natl Inst Stand Technol, 2020 Gu D.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
STUDY OF MECHANICAL PROPERTIES OF COMPACTED MATERIALS GROUND PADS AS RANDOM VARIABLES
Nauka ta progres transportu, 2010 The statistic analysis of variability values of mechanical characteristics of compacted soils is done. Also the laws of their distribution are determined. As a result, it is determined that for the deformation modulus, unit cohesion and internal friction
Yu. L. Vynnykov, M. O. Kharchenko
doaj
Modeling Directional Monotonicity in Sequence with Copulas
AxiomsIn this paper, we present the concept of being monotonic in sequence according to a specific direction for a collection of random variables. This concept broadens the existing notions of multivariate dependence, such as sequential left-tail and right ...
José Juan Quesada-Molina +1 more
doaj +1 more source
Expected Logarithm and Negative Integer Moments of a Noncentral χ2-Distributed Random Variable. [PDF]
Entropy (Basel), 2020 Moser SM.
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Measurement protocols, random-variable-valued measurements, and response process error: Estimation and inference when sample data are not deterministic. [PDF]
PLoS One, 2020 Kroc E.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source