Results 81 to 90 of about 3,344,527 (282)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
On infinite generativeness of quinary fractions in a class of probability transformers
Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2021 Background. The object of the research is the expressibility of rational probabilities by transforming random variables with distributions from some initial set by Boolean functions.
E.E. Trifonova
doaj +1 more source
Variable selection in multiple regression with random design
, 2015 We propose a method for variable selection in multiple regression with random predictors. This method is based on a criterion that permits to reduce the variable selection problem to a problem of estimating suitable permutation and dimensionality.
Mbina, Alban Mbina +2 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Estimation of the two-parameter Weibull distribution parameters using the coefficient of variation
Vojnotehnički Glasnik, 1996 This paper presents a method for estimating the reliability function parameters when reliability function is the 2-parametar Weibull regression. This model is often used in a reliability analysis in wide variety of situations to approximate successfully ...
Slavko Tomović
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Еstimation of randomity of generators of keys of the crypto system
Қарағанды университетінің хабаршысы. Математика сериясы, 2018 The aim of the study is to develop an algorithm for constructing an integer random variable representing random components of the keys of the RSA cryptosystem, and determining the table for the distribution of its probabilities.
M.T. Jenaliyev, А.Т. Nurtazin
doaj +1 more source
Piecewise linearisation of the first order loss function for families of arbitrarily distributed random variables [PDF]
, 2014 We discuss the problem of computing optimal linearisation parameters for the first order loss function of a family of arbitrarily distributed random variable.
Hendrix, Eligius M.T., Rossi, Roberto
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source