Results 91 to 100 of about 5,901,134 (247)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Interactive MATLAB-Based Demo Program for Sum of Independent Random Variables [PDF]

open access: yes, 2013
We present an interactive MATLAB-based demo program devoted to teaching undergraduate students the behavior of the sum of independent random variables. The user chooses the type of the variables, and the parameters of these variables. The sum is shown in
GORDANA JOVANOVIC DOLECEK
core  

Convergence of weighted sums of independent random variables and an extension to Banach space-valued random variables

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1979
Let {Xk} be independent random variables with EXk=0 for all k and let {ank:n≥1, k≥1} be an array of real numbers. In this paper the almost sure convergence of Sn=∑k=1nankXk, n=1,2,…, to a constant is studied under various conditions on the weights {ank ...
W. J. Padgett, R. L. Taylor
doaj   +1 more source

Results on Varextropy Measure of Random Variables. [PDF]

open access: yesEntropy (Basel), 2021
Vaselabadi NM   +3 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

On the strong convergence for weighted sums of asymptotically almost negatively associated random variables [PDF]

open access: yes, 2014
summary:Applying the moment inequality of asymptotically almost negatively associated (AANA, in short) random variables which was obtained by Yuan and An (2009), some strong convergence results for weighted sums of AANA random variables are obtained ...
Deng, Guangming   +3 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Explanation and Optimizing Multi‐Model Blending Algorithm Using Random Variables Theory

open access: yesGeophysical Research Letters
In this study, we modeled the multi‐model blending process using random variables and explicitly derived the distribution of the blended forecast error under the assumption of normally distributed errors.
Yu Wang   +6 more
doaj   +1 more source

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