Results 81 to 90 of about 5,901,134 (247)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

A note on the complete convergence for arrays of dependent random variables

Journal of Inequalities and Applications, 2011
A complete convergence result for an array of rowwise independent mean zero random variables was established by Kruglov et al. (2006). This result was partially extended to negatively associated and negatively dependent mean zero random variables by Chen
Sung Soo Hak
doaj  

Spectral Stochastic Finite Element Method for Electromagnetic Problems with Random Geometry

Electrical, Control and Communication Engineering, 2014
In electromagnetic problems, the problem geometry may not always be exactly known. One example of such a case is a rotating machine with random-wound windings.
Lehikoinen Antti
doaj   +1 more source

Ratio of Two Independent Lindley Random Variables. [PDF]

J Stat Theory Appl, 2022
Shakil M, Khadim A, Saghir A, Ahsanullah M, Golam Kibria BM, Ishaq Bhatti M.   +5 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Probabilistic Analysis of the Failure Time of Concrete-Filled Steel Tube (CFST) Columns under Post-Blast Fire Loading

Civil Engineering Dimension
This study examines the behavior and resistance of concrete-filled steel tube (CFST) columns under post-blast fire conditions, where prior explosions cause initial structural damage affecting fire performance.
Alireza Afaghi-Darabi, Majid Moradi, Sadegh Rezaei   +2 more
doaj   +1 more source

Reliability-Based Design Optimization Strategy for Soil Tillage Equipment Considering Soil Parameter Uncertainty

Advanced Engineering Research, 2016
The objective of this work is to provide an efficient tool of Reliability-Based Design Optimization (RBDO) for soil tillage machine design process in order to achieve designs with a required reliability (safety) level.
Ghias Mohamed Kharmanda, Imad Rezakalla Antypas   +1 more
doaj   +1 more source

Tsallis Entropy for Loss Models and Survival Models Involving Truncated and Censored Random Variables. [PDF]

Entropy (Basel), 2022
Preda V, Dedu S, Iatan I, Cernat ID, Sheraz M.   +4 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source