Results 81 to 90 of about 685,433 (277)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Tunable Persistent Random Walk in Swimming Droplets
Physical Review X, 2020 We characterize the motility of athermal swimming droplets within the framework of a persistent random walk. Just like active colloids, their trajectories can be modeled with a constant velocity V and a slow angular diffusion, but the random changes in ...
Adrien Izzet +6 more
doaj +1 more source
A New Random Walk for Replica Detection in WSNs. [PDF]
PLoS ONE, 2016 Wireless Sensor Networks (WSNs) are vulnerable to Node Replication attacks or Clone attacks. Among all the existing clone detection protocols in WSNs, RAWL shows the most promising results by employing Simple Random Walk (SRW).
Mohammed Y Aalsalem +5 more
doaj +1 more source
Critical dimensions for random walks on random-walk chains [PDF]
Physical Review E, 1996 The probability distribution of random walks on linear structures generated by random walks in $d$-dimensional space, $P_d(r,t)$, is analytically studied for the case $ \equiv r/t^{1/4}\ll1$. It is shown to obey the scaling form $P_d(r,t)= (r) t^{-1/2} ^{-2} f_d( )$, where $ (r)\sim r^{2-d}$ is the density of the chain.
Rabinovich S. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Random walks with random velocities
Physical Review E, 2008 We consider a random walk model that takes into account the velocity distribution of random walkers. Random motion with alternating velocities is inherent to various physical and biological systems. Moreover, the velocity distribution is often the first characteristic that is experimentally accessible. Here, we derive transport equations describing the
Zaburdaev, V. +2 more
openaire +4 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Bindweeds or random walks in random environments on multiplexed trees and their asympotics [PDF]
Discrete Mathematics & Theoretical Computer Science, 2003 We report on the asymptotic behaviour of a new model of random walk, we term the bindweed model, evolving in a random environment on an infinite multiplexed tree.The term multiplexed means that the model can be viewed as a nearest neighbours random walk ...
Mikhail Menshikov +2 more
doaj +1 more source
Random Walks in Random Environment [PDF]
Journal of Physics A: Mathematical and General, 2006 Random walks in random environments (RWRE's) have been a source of surprising phenomena and challenging problems since they began to be studied in the 70's. Hitting times and, more recently, certain regeneration structures, have played a major role in our understanding of RWRE's. We review these and provide some hints on current research directions and
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source