Results 61 to 70 of about 124,658 (311)

Quenched invariance principles for random walks and elliptic diffusions in random media with boundary [PDF]

open access: yes, 2014
Via a Dirichlet form extension theorem and making full use of two-sided heat kernel estimates, we establish quenched invariance principles for random walks in random environments with a boundary.
Croydon, David A.   +5 more
core   +1 more source

RANDOM WALK HYPOTHESIS IN FINANCIAL MARKETS [PDF]

open access: yesChallenges of the Knowledge Society, 2017
Random walk hypothesis states that the stock market prices do not follow a predictable trajectory, but are simply random. If you are trying to predict a random set of data, one should test for randomness, because, despite the power and complexity of the ...
Nicolae-Marius JULA, Nicoleta JULA
doaj  

Distributed Random Walks [PDF]

open access: yesJournal of the ACM, 2013
Performing random walks in networks is a fundamental primitive that has found applications in many areas of computer science, including distributed computing. In this article, we focus on the problem of sampling random walks efficiently in a distributed network and its applications.
Atish Das Sarma   +3 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Dirichlet random walk

open access: yesAnnales Henri Lebesgue, 2022
In this article we define and study a stochastic process on Galoisian covers of compact manifolds. The successive positions of the process are defined recursively by picking a point uniformly in the Dirichlet domain of the previous one.
Boulanger, Adrien, Glorieux, Olivier
openaire   +4 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

A Random Walk to Economic Freedom? [PDF]

open access: yesThe European Journal of Comparative Economics, 2013
Given the wide use of economic freedom in economic literature it is imperative to understand how economic freedom evolves. Results suggest that levels of economic freedom are dominated by random shocks. Using a test for stationarity devised by Westerlund
Witte, Mark David, Hefner, Frank
doaj  

Estimation of Parameters in the Random Walk Distribution [PDF]

open access: yesThe Egyptian Statistical Journal, 2001
The two parameters random walk distribution is defined and its characteristic are derived. Hazard function, mean, variance etc. are worked out for random walk distribution.
A. Sultan, A. Attia
doaj   +1 more source

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