Results 61 to 70 of about 685,433 (277)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
RANDOM WALK HYPOTHESIS IN FINANCIAL MARKETS [PDF]
Challenges of the Knowledge Society, 2017 Random walk hypothesis states that the stock market prices do not follow a predictable trajectory, but are simply random. If you are trying to predict a random set of data, one should test for randomness, because, despite the power and complexity of the ...
Nicolae-Marius JULA, Nicoleta JULA
doaj
Random walk centrality for temporal networks
New Journal of Physics, 2014 Nodes can be ranked according to their relative importance within a network. Ranking algorithms based on random walks are particularly useful because they connect topological and diffusive properties of the network. Previous methods based on random walks,
Luis E C Rocha, Naoki Masuda
doaj +1 more source
Ballistic random walks in random environment at low disorder
, 2003 We consider random walks in a random environment of the type p_0+\gamma\xi_z, where p_0 denotes the transition probabilities of a stationary random walk on \BbbZ^d, to nearest neighbors, and \xi_z is an i.i.d. random perturbation.
Sabot, Christophe
core +5 more sources
Random walks with barriers [PDF]
Nature Physics, 2011 Restrictions to molecular motion by barriers (membranes) are ubiquitous in porous media, composite materials and biological tissues. A major challenge is to characterize the microstructure of a material or an organism nondestructively using a bulk transport measurement.
Novikov, Dmitry S. +3 more
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Non symmetric random walk on infinite graph [PDF]
Opuscula Mathematica, 2011 We investigate properties of a non symmetric Markov's chain on an infinite graph. We show the connection with matrix valued random walk polynomials which satisfy the orthogonality formula with respect to non a symmetric matrix valued measure.
Marcin J. Zygmunt
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Noisy cyclic quantum random walk
APL QuantumWe explore static noise in a discrete quantum random walk over a homogeneous cyclic graph, focusing on the spectral and dynamical properties of the system.
Gilberto Juárez Rangel +1 more
doaj +1 more source
Lengths and heights of random walk excursions [PDF]
Discrete Mathematics & Theoretical Computer Science, 2003 Consider a simple symmetric random walk on the line. The parts of the random walk between consecutive returns to the origin are called excursions. The heights and lengths of these excursions can be arranged in decreasing order.
Endre Csáki, Yueyun Hu
doaj +1 more source