Results 71 to 80 of about 125,107 (311)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A Random Walk to Economic Freedom? [PDF]
The European Journal of Comparative Economics, 2013 Given the wide use of economic freedom in economic literature it is imperative to understand how economic freedom evolves. Results suggest that levels of economic freedom are dominated by random shocks. Using a test for stationarity devised by Westerlund
Witte, Mark David, Hefner, Frank
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Estimation of Parameters in the Random Walk Distribution [PDF]
The Egyptian Statistical Journal, 2001 The two parameters random walk distribution is defined and its characteristic are derived. Hazard function, mean, variance etc. are worked out for random walk distribution.
A. Sultan, A. Attia
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Tunable Persistent Random Walk in Swimming Droplets
Physical Review X, 2020 We characterize the motility of athermal swimming droplets within the framework of a persistent random walk. Just like active colloids, their trajectories can be modeled with a constant velocity V and a slow angular diffusion, but the random changes in ...
Adrien Izzet +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Non-homogeneous random walks with non-integrable increments and heavy-tailed random walks on strips [PDF]
, 2012 We study asymptotic properties of spatially non-homogeneous random walks with non-integrable increments, including transience, almost-sure bounds, and existence and non existence of moments for first-passage and last-exit times.
MacPhee, Iain M. +9 more
core +2 more sources
Self-avoiding pruning random walk on signed network
New Journal of Physics, 2019 A signed network represents how a set of nodes are connected by two logically contradictory types of links: positive and negative links. In a signed products network, two products can be complementary (purchased together) or substitutable (purchased ...
Huijuan Wang +3 more
doaj +1 more source
The Annals of Probability, 1984 We consider random walks on lattices with finite memory and a finite number of possible steps. Using a local limit theorem, we generalize Polya's theorem to such walks, describe how to compute tail probabilities when the number of steps is large, and obtain asymptotic estimates for the average number of points visited.
Bender, Edward A., Richmond, L. Bruce
openaire +2 more sources