Results 161 to 170 of about 702,734 (359)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Combined oral and nasal beclomethasone diproprionate in children with atopic eczema: a randomised controlled trial. [PDF]

, 1984
R J Heddle, J F Soothill, C J Bulpitt, David J. Atherton   +3 more
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Double-Blind Randomised Controlled Trial of Folate Treatment before Conception to Prevent Recurrence of Neural-Tube Defects [PDF]

, 1981
K. M. Laurence, Nansi James, Mary Helen Miller, G. B. Tennant, H. Campbell   +4 more
openalex   +1 more source

What is a randomised controlled trial?

Epidemiologia e Psichiatria Sociale, 2009
CIPRIANI, Andrea, Geddes JR
openaire   +5 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Effects of stimulating single acupoint and combination acupoints on diabetic gastroparesis: A randomised controlled trial study

Journal of Traditional and Complementary Medicine
Background and aim: The most effective among the acupoints remains to be determined for treating diabetic gastroparesis (DGP). This study aimed to compare single and combination acupoints for their effectiveness in DGP.
Renming Liu, Min He, Xuewei Zhao, Mengmeng Sun, Jiazhen Cao, Xinyue Wang, Xingbang Wang, Shuming Zhao, Fuchun Wang, Tie Li   +9 more
doaj  

Randomised controlled trial of fish oil supplement to treat cancer cachexia [PDF]

, 2015
Patients with advanced cancer often suffer from cachexia, a debilitating and complex extreme weight loss syndrome which is also associated with shorter survival times.
Baughan, C, Dean, Taraneh, Dewey, Ann, Higgins, Bernard Robert, Kilburn, Sally Anne, Stores, Rebecca Jane   +5 more
core   +1 more source

Role of corticosteroid Injections versus Physiotherapy for the Treatment of Painful Stiff Shoulder: A Randomised Control Trial

, 1970
Shamsun Nahar, Monirul Islam, Maliha Hakim, Akm Anwar Ullah   +3 more
openalex   +2 more sources

A randomised controlled trial of adenine arabinoside 5′-monophosphate (ARA-AMP) in chronic hepatitis B virus infection [PDF]

, 1986
Ian Weller
openalex   +1 more source