Results 61 to 70 of about 667,561 (138)

Randomised controlled trials are important

BMJ, 1999
EDITOR—Cranberg's arguments against controlled trials and in favour of historical controls supported by data on matching for known risk factors are seriously flawed.1 There are at least four fallacies. Firstly, the matching procedures …
openaire   +4 more sources

Establishing cost-effectiveness of genetic targeting of cancer therapies [PDF]

, 2011
The clinical benefit of a new genomic instrument, the 70-gene signature for breast cancer patients, is being evaluated in a randomised clinical trial. The early, controlled implementation process is supported by a Constructive Technology Assessment to ...
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +1 more source

Double Blind, Randomised Controlled Trial [PDF]

, 2015
Purpose Surgical patients are at high risk for developing infectious complications and postoperative delirium. Prolonged infections and delirium result in worse outcome. Granulocyte-macrophage colony-stimulating factor (GM- CSF) and influenza vaccination
Bahra, Marcus, Haefen, Clarissa von, Lachmann, Gunnar, Luetz, Alawi, Meisel, Christian, Paupers, Marco, Renius, Markus, Schiemann, Alexander, Spies, Claudia, Wernecke, Klaus-Dieter   +9 more
core   +1 more source

Undertaking a randomised controlled trial in the police setting : methodological and practical challenges [PDF]

, 2017
BACKGROUND: There has been an increased drive towards Evidence Based Policing in recent years. Unlike in other public sector services, such as health and education, randomised controlled trials in the police setting are relatively rare.
Booth, Alison, Fairhurst, Caroline, Hewitt, Catherine, McDaid, Catriona, Parker, Adwoa, Payne, Rebecca, Reed, Helen, Scantlebury, Arabella, Scott, William J, Torgerson, David   +9 more
core   +2 more sources

The DURATIONS randomised trial design: estimation targets, analysis methods and operating characteristics [PDF]

arXiv, 2020
Background. Designing trials to reduce treatment duration is important in several therapeutic areas, including TB and antibiotics. We recently proposed a new randomised trial design to overcome some of the limitations of standard two-arm non-inferiority trials.
arxiv  

Repetitive arm functional tasks after stroke (RAFTAS): a pilot randomised controlled trial [PDF]

, 2016
Background Repetitive functional task practise (RFTP) is a promising treatment to improve upper limb recovery following stroke. We report the findings of a study to determine the feasibility of a multi-centre randomised controlled trial to evaluate ...
A Pollock, A Pollock, A Turton, B French, B Langhammer, B Langhammer, C Bradley, C Donaldson, CJ Winstein, F Duncan, F Wijck van, FM Nouri, G Demeurisse, G Kwakkel, G Kwakkel, GA Lancaster, H Nakayama, H Rodgers, J Bamford, J Blennerhassett, J Higgins, JE Harris, JH Carr, JH Lee Van der, JM Bamford, KN Arya, L Shaw, L Thabane, P Craig, P Langhorne, PM Vliet van, R Schmidt, RC Lyle, RW Bohannon, S Pandian, T Brott, TC Hoffman, V Pomeroy   +37 more
core   +3 more sources

Is the randomised controlled trial the best?

South African Journal of Obstetrics and Gynaecology, 2014
Different study formats are preferred for different research objectives. Randomised controlled trials (RCTs) have a greater ability to test efficacy than other methods, but RCTs can have many limitations. These limitations should be explored, assessed and exposed.
openaire   +3 more sources

An evaluation of the effectiveness of the Lidcombe program of early stuttering intervention [PDF]

, 2005
This thesis presents a randomised controlled trial of the Lidcombe Program of Early Stuttering Intervention. The Lidcombe Program was developed for the treatment of stuttering in preschool-age children.
Jones, Mark A
core   +1 more source

The combined diabetes and renal control trial (C-DIRECT) - a feasibility randomised controlled trial to evaluate outcomes in multi-morbid patients with diabetes and on dialysis using a mixed methods approach [PDF]

, 2019
Background: This cluster randomised controlled trial set out to investigate the feasibility and acceptability of the “Combined Diabetes and Renal Control Trial” (C-DIRECT) intervention, a nurse-led intervention based on motivational interviewing and self-
AM Jacobson, AS Zigmond, AY Lai, C. G. Chua, CA Eigenmann, CSY Goh, DJ Toobert, E Salsberg, E. Y. H. Khoo, EA Bayliss, EA Beverly, EA Kerr, F Willingham, GW Welch, H Knight, H Vlaminck, I Bjelland, IM Stratton, IR White, JY Chen, K Griva, K. Griva, KR Lorig, L Bramley, M Anees, M. Nandakumar, M. Rajeswari, MA Powers, ME Charlson, MF Huang, MJ Davies, P Craig, R Schwarzer, RD Hays, RH Osborne, RK Yoong, S Newman, S. P. Newman, SL Norris, T Washington, V Braun, V. Y. W. Lee, WH Polonsky, Y-Q Huang, Y. T. D. Choong, YH Tang, Z. S. Goh   +46 more
core   +1 more source

Establishing cost-effectiveness of genetic targeting of cancer therapies\ud [PDF]

, 2008
The clinical benefit of a new genomic instrument, the 70-gene signature\ud for breast cancer patients, is being evaluated in a randomised clinical\ud trial.
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +2 more sources