Results 91 to 100 of about 554,861 (311)

Chinese herbal medicine for atopic eczema [PDF]

, 2009
Background: Traditional Chinese herbal mixtures have been used to treat atopic eczema for many years. Their efficacy has attracted public attention and recently some clinical trials have been undertaken.
Gu, X, Li, C, Pang, C, Williams, H, Xue, C, Yang, W   +5 more
core  

A systematic review of non-pharmacological interventions for primary Sjögren’s syndrome [PDF]

, 2015
The objective of this systematic review was to assess the efficacy of non-pharmacological interventions for the management of primary Sjögren’s syndrome.
Cockshott, Ervin, Fox, Goodchild, Higgins, Julia L. Newton, Katherine H. O. Deane, Katie L. Hackett, Lefebvre, Manthorpe, O’Connor, Patel, Tim Rapley, Tobon, Valim, van Leeuwen, Victoria Strassheim, Vincent Deary, Wan-Fai Ng, WHO   +19 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Identifying important barriers to recruitment of patients in randomised clinical studies using a questionnaire for study personnel

Trials, 2019
Background Many randomised controlled trials (RCT) fail to meet their recruitment goals. Study personnel play a key role in recruitment. The aim of this study was to identify successful strategies that study personnel consider to be important in patient ...
Eva Isaksson, Per Wester, Ann Charlotte Laska, Per Näsman, Erik Lundström   +4 more
doaj   +1 more source

The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial [PDF]

, 2013
Background: Group-based social skills training (SST) has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD). To date, no sufficiently powered randomised controlled trial has been performed to establish
Bender, Stephan, Cholemkery, Hannah, Elsuni, Leyla, Freitag, Christine M., Kieser, Meinhard, Kroeger, Anne K., Kunz, Cornelia Ursula   +6 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Improved dietary intake among overweight and obese children followed from 8 to 12 years of age in a randomised controlled trial

Journal of Nutritional Science, 2012
More knowledge about improving dietary intake in secondary preventive actions against childhood overweight and obesity is needed. The objective was to evaluate the impact of a 2-year intervention on energy, macronutrient and food intake of overweight and
Maria Waling, Christel Larsson
doaj   +1 more source

Physical therapies for reducing and controlling lymphoedema of the limbs. [PDF]

, 2008
Background Lymphoedema is the accumulation of excess fluid in the body caused by obstruction of the lymphatic drainage mechanisms. Management involves decongesting the reduced lymphatic pathways in order to reduce the size of the limb.
Ahmed, Andersen, Badger, Badger, Bergan, Bertelli, Carroll, Didem, Dini, Erickson, Foldi, Harris, Hornsby, Irdesel, Johansson, Johansson, Kligman, Levick, McKenzie, McNeely, Moffatt, Mortimer, Moseley, Petrek, Sitzia, Sitzia, Szuba, Szuba, Tobin, Wilburn, Williams   +30 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Activities to support the implementation of complex interventions as part of routine care: a review of the quality of reporting in cluster randomised controlled trials [PDF]

, 2015
Objective: To review a sample of cluster randomised controlled trials and explore the quality of reporting of (1) enabling or support activities provided to the staff during the trial, (2) strategies used to monitor fidelity throughout the trial and (3 ...
Boutron, Campbell, Chalmers, Chan, Craig, Douet, Flay, Gartlehner, Glasgow, Glasziou, Hoffmann, Hoffmann, Moore, Papadakis, Schroter, Schulz, Thorpe, Wells   +17 more
core   +2 more sources