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[Randomised controlled trials].

Wiener medizinische Wochenschrift (1946), 2008
Nowadays the Randomised Controlled Trial (RCT) is seen as the gold standard for estimating the effectiveness of an observed intervention, achieving the highest hierarchy of evidence of primary research settings. Its study design basically includes two groups of patients, an intervention group and a control group; patients are randomly allocated to ...
Philipp, Mad   +2 more
openaire   +1 more source

Rethinking pragmatic randomised controlled trials: introducing the "cohort multiple randomised controlled trial" design

BMJ, 2010
Pragmatic trials are important for informing routine clinical practice, but current designs have shortcomings. Clare Relton and colleagues outline the new “cohort multiple randomised controlled trial” design, which could help address the problems associated with existing ...
Clare, Relton   +3 more
openaire   +2 more sources

Randomised controlled trial

TVZ - Verpleegkunde in praktijk en wetenschap, 2022
Dirk Ubbink, Hester Vermeulen
openaire   +1 more source

Randomised controlled trials: subgroup analyses

BMJ, 2014
The effectiveness of wound edge protection devices in reducing surgical site infection after abdominal surgery was investigated. A randomised controlled trial was undertaken. The intervention was standard intraoperative care plus use of a wound edge protection device during the intra-abdominal part of the operation.
openaire   +2 more sources

Randomised controlled trials: understanding power

BMJ, 2015
The effects of manual lymph drainage on the development of lymphoedema related to breast cancer were investigated using a randomised controlled trial.1 The intervention was a six months’ treatment programme consisting of guidelines about prevention of lymphoedema, exercise therapy, and manual lymph drainage.
openaire   +2 more sources

Randomised controlled trials: understanding confounding

BMJ, 2015
Researchers assessed the effectiveness of an exercise programme in reducing injurious falls among women at increased risk of falls and injuries. A multicentre parallel group randomised controlled trial study design was used. The intervention consisted of weekly supervised group sessions of progressive balance training offered in community based ...
openaire   +2 more sources

Cluster randomised controlled trials

2018
A methodological guide from Cochrane Consumers and Communication about analysing cluster randomised controlled ...
Cochrane Consumers And Communication La Trobe University   +2 more
openaire   +1 more source

Pilot Randomised Controlled Trials

2008
Pilot studies are usually very helpful precursors to definitive RCTs. Possibly the first educational RCT (Walters, 1931), which looked at the role of counselling among undergraduate students, was later described as an ‘introductory experiment’ (Walters, 1932). We would now describe this trial as a pilot study.
David J. Torgerson, Carole J. Torgerson
openaire   +1 more source

Older adult participation in cancer clinical trials: A systematic review of barriers and interventions

Ca-A Cancer Journal for Clinicians, 2021
Mina S Sedrak   +2 more
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

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