Topical analgesia for acute otitis media [PDF]
BACKGROUND: Acute otitis media (AOM) is a spontaneously remitting disease for which pain is the most distressing symptom. Antibiotics are now known to have less benefit than previously assumed.OBJECTIVES: To assess the effectiveness of topical analgesia ...
Del Mar, C +4 more
core +1 more source
Objective To systematically summarise and evaluate the existing evidence on the effect of diet on the management of type 2 diabetes and prevention of complications.Design Umbrella review of systematic reviews with meta-analyses of randomised controlled ...
Lukas Schwingshackl +5 more
doaj +1 more source
A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis [PDF]
Purpose: Surgical arteriovenous fistula (AVF) or graft (AVG) is preferred to a central venous catheter for dialysis access. Surgical access may suffer thrombosis early after placement and systemic anticoagulation during surgical access formation may ...
Carradice, Daniel +5 more
core +1 more source
Surgical interventions for the early management of Bell's palsy [PDF]
Background: Bell's palsy is an acute paralysis of one side of the face of unknown aetiology. Bell's palsy should only be used as a diagnosis in the absence of all other pathology.
Adour +30 more
core +3 more sources
A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint
Background It has been argued that true endpoints (or ‘hard’ endpoints) for clinical trials, which are meaningful to clinicians, researchers and patients alike, are limited to those that measure health status, survival and cost.
M. J. Campbell +2 more
doaj +1 more source
Increasing participation of cancer patients in randomised controlled trials: a systematic review [PDF]
Background: There are many barriers to patient participation in randomised controlled trials of cancer treatments. To increase participation in trials, strategies need to be identified to overcome these barriers.
Alison Eastwood +5 more
core +3 more sources
Gross Domestic Product (GDP) and productivity of schizophrenia trials: an ecological study [PDF]
The 5000 randomised controlled trials (RCTs) in the Cochrane Schizophrenia Group's database affords an opportunity to research for variables related to the differences between nations of their output of schizophrenia trials.
B Thornley +11 more
core +3 more sources
A systematic review of how studies describe educational interventions for evidence-based practice:Stage 1 of the development of a reporting guideline [PDF]
Background The aim of this systematic review was to identify which information is included when reporting educational interventions used to facilitate foundational skills and knowledge of evidence-based practice (EBP) training for health ...
Galipeau, James +8 more
core +2 more sources
Background and objectives: Journal articles describing randomised controlled trials (RCTs) are not optimally reported, often missing crucial details that ensure transparency and reproducibility.
Michael Schlussel +3 more
doaj +1 more source
Video assisted thoracic surgery for treatment of pneumothorax and lung resections: systematic review of randomised clinical trials [PDF]
<b>Objectives</b> To determine if video assisted thoracic surgery is associated with better clinical outcomes than thoracotomy for three common procedures: surgery for pneumothorax, minor resections, and lobectomy.
Lewsey, J. +3 more
core +3 more sources

