Results 51 to 60 of about 554,861 (311)

Frailty in randomised controlled trials for dementia or mild cognitive impairment measured via the frailty index: prevalence and prediction of serious adverse events and attrition

Alzheimer’s Research & Therapy, 2023
Background Frailty and dementia have a bidirectional relationship. However, frailty is rarely reported in clinical trials for dementia and mild cognitive impairment (MCI) which limits assessment of trial applicability.
Heather Wightman, Terry J. Quinn, Frances S. Mair, Jim Lewsey, David A. McAllister, Peter Hanlon   +5 more
doaj   +1 more source

Managing behavioural and psychological symptoms in community dwelling older people with dementia:1. A systematic review of the effectiveness of interventions [PDF]

, 2018
© 2018 The Author(s) This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence CC BY 4.0 (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any
Ashaye, Kunle, Braun, Andreas, Dickinson, Angela, Gage, Heather, Goodman, Claire, Hamilton, Laura, Iliffe , Steve, Manthorpe , Jill, Trivedi, Daksha   +8 more
core   +2 more sources

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

Pediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard, Anni Young Lundgaard, Laura Ann Rechner, Danijela Dejanovic, Hanne Krogh Rose, Jolanta Hansen, Leila Vaalavirta, Miia Mokka, Marianne Aznar, Peder Skov Wehner, Lisa Lyngsie Hjalgrim, Maja Vestmø Maraldo   +11 more
wiley   +1 more source

Trials Methodology Research: what is it and why should India invest in it?

The Lancet Regional Health - Southeast Asia
Summary: This Viewpoint presents an overview of trials methodology research (TMR) and the case for investing in TMR in India. Randomised controlled trials and other types of clinical research inform evidence-based medicine, but this endeavour is ...
Sangeetha Paramasivan, Anant Bhan, Rashmi Rodrigues, Usha Menon   +3 more
doaj   +1 more source

Systematic review and meta-analyses of psychosocial interventions for veterans of the military [PDF]

European Journal of Psychotraumatology, 2012
Background: The efficacy of psychosocial therapies for common mental health disorders in veterans is unclear and requires further examination. Method: Systematic review and meta-analyses of randomised controlled trials (RCTs).
Neil J. Kitchiner, Neil P. Roberts, David Wilcox, Jonathan I. Bisson   +3 more
doaj   +1 more source

Pulsed electromagnetic energy treatment offers no clinical benefit in reducing the pain of knee osteoarthritis: a systematic review [PDF]

, 2006
Background The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF).
AD Woolf, AR Jadad, Centre for Health Economics University of York, Christopher James McCarthy, CJ McCarthy, DH Trock, DH Trock, E Roddy, G Thamsborg, JA Klaber Moffett, Jacqueline Anne Oldham, JE Ware, JM Hulme, JP Van Nguyen, Michael James Callaghan, MJ Callaghan, N Bellamy, N Pipitone, R Marks, RF Meenan, TD Spector, TM Zizic, Y Laufer   +22 more
core   +5 more sources

Supported employment: randomised controlled trial [PDF]

British Journal of Psychiatry, 2010
BackgroundThere is evidence from North American trials that supported employment using the individual placement and support (IPS) model is effective in helping individuals with severe mental illness gain competitive employment. There have been few trials in other parts of the world.AimsTo investigate the effectiveness and cost-effectiveness of IPS in ...
Howard, Louise M., Heslin, Margaret, Leese, Morven, McCrone, Paul, Rice, Christopher, Jarrett, Manuela, Spokes, Terry, Huxley, Peter, Thornicroft, Graham   +8 more
openaire   +4 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Study protocol for a randomised controlled trial of invasive versus conservative management of primary spontaneous pneumothorax [PDF]

, 2016
INTRODUCTION: Current management of primary spontaneous pneumothorax (PSP) is variable, with little evidence from randomised controlled trials to guide treatment.
Asha, Stephen E., Ball, Emma L., Beasley, Richard, Brown, Simon G. A., Egerton-Warburton, Diana, Jones, Peter G., Keijzers, Gerben, Kinnear, Frances B., Kwan, Ben C. H., Lee, Y. C. Gary, Perrin, Kyle, PSP Study Group, Read, Catherine A., Simpson, Graham, Smith, Julian A., Summers, Quentin A   +15 more
core   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source