Results 61 to 70 of about 554,861 (311)

Multi-centric clinic trials in evidence-based research – A narrative review on the Indian scenario

Journal of Family Medicine and Primary Care, 2023
Evidence-based health care is gaining prominence since the past many decades. The ultimate goal of evidence-based medicine is providing the best available treatment to patients.
Deepa J. Patil, Tarun Vyas, Ajay P. S. Kataria, Rajan Rajput, Albert Ashem, Mukesh Kumar   +5 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

International multi-stakeholder consensus statement on clinical trial integrity

Middle East Fertility Society Journal
Objective To prepare a set of statements for randomised clinical trials (RCT) integrity through an international multi-stakeholder consensus. Methods The consensus was developed via multi-country multidisciplinary stakeholder group composition and ...
Khalid Saeed Khan, for the Cairo Consensus Group on Research Integrity   +1 more
doaj   +1 more source

Landscape of Nutrition- or Diet-Related Randomised Controlled Trials: Data from Protocols Published between 2012 and 2022

Proceedings
Background and aims: As part of a project to consolidate reporting guidance for randomised controlled trials (RCTs), protocols of RCTs, and systematic reviews of nutritional interventions, it was important to understand the nutritional interventions ...
Michael Schlussel, Flavia Moraes, Simone Bernardes, Solange Durão   +3 more
doaj   +1 more source

Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis

Trials, 2022
Background Recruiting patients to randomised controlled trials (RCTs) is often reported to be challenging, and the evidence base for effective interventions that could be used by staff (recruiters) undertaking recruitment is lacking.
Nicola Farrar, Daisy Elliott, Catherine Houghton, Marcus Jepson, Nicola Mills, Sangeetha Paramasivan, Lucy Plumb, Julia Wade, Bridget Young, Jenny L. Donovan, Leila Rooshenas   +10 more
doaj   +1 more source

Randomised controlled trials in hand surgery: a scoping review

BMJ Open, 2022
Objectives To identify the evidence gaps that exist regarding the efficacy or effectiveness of hand surgery.Setting A scoping review. We systematically searched MEDLINE, Embase and CENTRAL databases to identify all hand surgical randomised controlled ...
Rachelle Buchbinder, Teemu Karjalainen, Jarkko Jokihaara, Juuso Heikkinen, Soumen Das De, Kati Jaatinen   +5 more
doaj   +1 more source

Decompressive surgery for treating nerve damage in leprosy. A Cochrane review. [PDF]

, 2009
OBJECTIVE: Decompressive surgery is used for treating nerve damage in leprosy. We assessed the effectiveness of decompressive surgery for patients with nerve damage due to leprosy.
Agarwal, A. (Anita), Richardus, J.H. (Jan Hendrik), Schreuders, A.R. (Ton), Theuvenet, W.J. (Willem), Veen, H.H.J. (Natasja) van   +4 more
core  

Staff-led interventions for improving oral hygiene in patients following stroke [PDF]

, 2010
Background For people with limitations due to neurological conditions such as stroke, the routine practice of oral care may become a challenge. Evidence-based supported oral care intervention is essential for this patient group. Objectives To compare the
Brady, Marian C., Furlanetto, Denise, Hunter, Romana, Lewis, Steff C., Milne, Vikki   +4 more
core   +3 more sources

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Registry-based randomised controlled trials: conduct, advantages and challenges—a systematic review

Trials
Background Registry-based randomised controlled trials (rRCTs) have been described as pragmatic studies utilising patient data embedded in large-scale registries to facilitate key clinical trial procedures including recruitment, randomisation and the ...
Frances Shiely, Niamh O Shea, Ellen Murphy, Joseph Eustace   +3 more
doaj   +1 more source