Results 231 to 240 of about 8,079,813 (317)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.

JAMA Pediatr
Carter PM, Resnicow K, Stallworth P, Goldstick J, Carrillo A, Seewald L, Cunningham RM, Massey L, Battisti K, Schoener B, Walton MA.   +10 more
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial.

JAMA Intern Med
Leong DP, Higano C, Cano Garcia C, Fradet V, Siemens DR, Niazi T, Shayegan B, Guha A, Cirne F, Selvanayagam JB, Violette PD, Valle FH, Lavallée LT, Duceppe E, Anderson P, Xavier D, Lopez-Lopez JP, Villareal Trujillo N, Galapo Kann A, Piccoli RK, Mourtzakis M, Sarid D, Narasimha S, Luke PPW, Hajjar LA, Lukka H, Klotz L, Balasubramanian K, Mian R, Agapay S, Rangarajan S, Karampatos S, Ng KKH, Avezum A, Devereaux PJ, Pinthus JH, RADICAL PC Investigators.   +36 more
europepmc   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Transoral Ultrasound in the Diagnostic Workup of Peritonsillar Abscess-A Randomized Clinical Trial. [PDF]

Laryngoscope
Todsen T, Stage MG, Melchiors J, Mejdahl M, Posselt AP, Madsen AR, Hahn CH, Godballe C, Michaelsen SH.   +8 more
europepmc   +1 more source

Desmodium styracifolium Total Flavone Capsules for Urolithiasis: A Phase 3 Randomized Clinical Trial.

JAMA Netw Open
Wang D, Zhang S, Zhao W, Chen S, Zhou W, Xue Y, He Z, Yang M, Chen L, Zhu S.   +9 more
europepmc   +1 more source

Preschool Physical Activity Policy and Children's Physical Activity: A Pragmatic Cluster Randomized Clinical Trial.

JAMA Netw Open
Chen C, Migueles JH, Ahlqvist VH, Campos-Garzón P, Henriksson P, Neovius M, Galanti MR, Kosidou K, Orsini N, Lager A, Berglind D.   +10 more
europepmc   +1 more source

Interleukin 6 as a Treatment Target for Depression: A Proof-of-Concept Randomized Clinical Trial.

JAMA Psychiatry
Foley ÉM, Turner N, Margelyte R, Jones HJ, Kaser M, Lewis G, Jones PB, Khandaker GM.   +7 more
europepmc   +1 more source

Prophylactic vs Therapeutic Anticoagulation in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

JAMA Netw Open
Karakas M, Nicolay SS, Wichmann D, Schmiedel S, Addo MM, Nosko A, Lund N, Shrivastava A, Pink I, Duerschmied D, Gauchel N, Schnoy E, Pape UF, Bein B, Brasch P, Arnold D, Maevers K, Rasch S, Erber J, Lahmer T, Zeller T, Langer F, Ozga AK, Suling A, Zapf A, Jarczak D, Kluge S.   +26 more
europepmc   +1 more source