Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
A randomized controlled trial of a trauma-informed smartphone application in reducing firefighters' mental health symptoms. [PDF]
Varker T +10 more
europepmc +1 more source
Definition of a randomized controlled trial
Beckerman, Heleen +2 more
openaire +3 more sources
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Effect of Lutein Ester Supplement on Choroidal Thickness in Children: A Randomized Controlled Trial. [PDF]
Li T +18 more
europepmc +1 more source
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones +10 more
wiley +1 more source
Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial [PDF]
Ruth Bolier +7 more
openalex +1 more source
Time Trends and Predictors of Gout Remission Over 6 Years
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah +5 more
wiley +1 more source
Development and External Validation of a Genetic Risk Score for Pain in Rheumatoid Arthritis
Objective Several single‐nucleotide polymorphisms (SNPs) have been associated with chronic pain syndromes. Our objective was to determine whether genetic variants are associated with pain and disease activity in rheumatoid arthritis (RA). Methods Participants were included from two independent RA cohorts: FORWARD (National Databank for Rheumatic ...
Katie J. McMenamin +15 more
wiley +1 more source
Telenursing in care education for caregivers of psoriasis patients: a protocol for a randomized controlled trial. [PDF]
Akbari A +2 more
europepmc +1 more source

