Results 231 to 240 of about 4,106,658 (410)

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Doubly robust omnibus sensitivity analysis of externally controlled trials with intercurrent events [PDF]

arXiv
Externally controlled trials are crucial in clinical development when randomized controlled trials are unethical or impractical. These trials consist of a full treatment arm with the experimental treatment and a full external control arm. However, they present significant challenges in learning the treatment effect due to the lack of randomization and ...
arxiv  

A double-masked placebo-controlled trial of azithromycin to prevent child mortality in Burkina Faso, West Africa: Community Health with Azithromycin Trial (CHAT) study protocol. [PDF]

, 2019
BACKGROUND:Biannual, mass azithromycin distribution has previously been shown to reduce all-cause child mortality in sub-Saharan Africa. Subgroup analysis suggested that the strongest effects were in the youngest children, leading to the hypothesis that ...
Bagagnan, Cheik, Boudo, Valentin, Bountogo, Mamadou, Brogdon, Jessica M, Bärnighausen, Till, Coulibaly, Boubacar, Doan, Thuy, Lebas, Elodie, Lietman, Thomas M, Lin, Ying, Oldenburg, Catherine E, Ouattara, Mamadou, Porco, Travis C, Sié, Ali, Étude CHAT Study Group   +14 more
core  

Treatment of supracondylar fracture of the humerus (type IIB and III) in children: A prospective randomized controlled trial comparing two methods

, 1970
Sharad Pandey, D Shrestha, Mathis Görg, G.R. Singh, MP Singh   +4 more
openalex   +2 more sources

Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: Synopsis of three randomized controlled trials [PDF]

, 1982
B. Schöning, W Lorenz, Α. Doenicke
openalex   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Randomized controlled trial of transfer factor in stage II malignant melanoma [PDF]

, 1983
Ronald M. Bukowski, S. Deodhar, James S. Hewlett, Richard L. Greenstreet   +3 more
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

A randomized controlled trial comparing short-term versus long-term catheterization after vaginal prolapse surgery

, 1970
Nupur Thakur, Geeta Gurung, Ashma Rana
openalex   +2 more sources

A European multicenter randomized controlled trial of single dose surfactant therapy for idiopathic respiratory distress syndrome [PDF]

, 1990
Jeffrey D. Horbar, Roger F. Soll, Hartmut Schächinger, G Kewitz, Hans Versmold, Wolfgang Lindner, G. Duc, D Mieth, O Linderkamp, E. P. Zilow, P. Lemburg, V von Loewenich, Marek Brand, I Minoli, Guido E. Moro, K Riegel, R. Roos, Laurence Weiss, Jerold F. Lucey   +18 more
openalex   +1 more source